Cellular resistance to an oncolytic virus is driven by chronic activation of innate immunity

The emergence of cellular resistances to oncolytic viruses is an underexplored process that could compromise the efficacy of cancer virotherapy. Here, we isolated and characterized B16 mouse melanoma cells that evolved resistance to an oncolytic vesicular stomatitis virus (VSV-D51). RNA-seq revealed...

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Detalles Bibliográficos
Autores principales: Larrieux, Alejandra, Sanjuán, Rafael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9794979/
https://www.ncbi.nlm.nih.gov/pubmed/36590165
http://dx.doi.org/10.1016/j.isci.2022.105749

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9794979/
https://www.ncbi.nlm.nih.gov/pubmed/36590165
http://dx.doi.org/10.1016/j.isci.2022.105749

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