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Cellular resistance to an oncolytic virus is driven by chronic activation of innate immunity
The emergence of cellular resistances to oncolytic viruses is an underexplored process that could compromise the efficacy of cancer virotherapy. Here, we isolated and characterized B16 mouse melanoma cells that evolved resistance to an oncolytic vesicular stomatitis virus (VSV-D51). RNA-seq revealed...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Elsevier
2022
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9794979/ https://www.ncbi.nlm.nih.gov/pubmed/36590165 http://dx.doi.org/10.1016/j.isci.2022.105749 |