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COVID‐associated non‐vasculitic thrombotic retiform purpura of the face and extremities: A case report

SARS‐CoV‐2 infection can manifest many rashes. However, thrombotic retiform purpura rarely occurs during COVID‐19 illness. Aggressive anti‐COVID‐19 therapy with a high‐dose steroid regimen led to rapid recovery. This immunothrombotic phenomenon likely represents a poor type 1 interferon response and...

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Detalles Bibliográficos
Autores principales: Bunch, Connor M., Zackariya, Nuha, Thomas, Anthony V., Langford, Jack H., Aboukhaled, Michael, Thomas, Samuel J., Ansari, Aida, Patel, Shivani S., Buckner, Hallie, Miller, Joseph B., Annis, Christy L., Quate‐Operacz, Margaret A., Schmitz, Leslie A., Pulvirenti, Joseph J., Konopinski, Jonathan C., Kelley, Kathleen M., Hassna, Samer, Nelligan, Luke G., Walsh, Mark M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9795088/
https://www.ncbi.nlm.nih.gov/pubmed/36590660
http://dx.doi.org/10.1002/ccr3.6790
Descripción
Sumario:SARS‐CoV‐2 infection can manifest many rashes. However, thrombotic retiform purpura rarely occurs during COVID‐19 illness. Aggressive anti‐COVID‐19 therapy with a high‐dose steroid regimen led to rapid recovery. This immunothrombotic phenomenon likely represents a poor type 1 interferon response and complement activation on the endothelial surface in response to acute infection.