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COVID‐associated non‐vasculitic thrombotic retiform purpura of the face and extremities: A case report
SARS‐CoV‐2 infection can manifest many rashes. However, thrombotic retiform purpura rarely occurs during COVID‐19 illness. Aggressive anti‐COVID‐19 therapy with a high‐dose steroid regimen led to rapid recovery. This immunothrombotic phenomenon likely represents a poor type 1 interferon response and...
Autores principales: | , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9795088/ https://www.ncbi.nlm.nih.gov/pubmed/36590660 http://dx.doi.org/10.1002/ccr3.6790 |
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author | Bunch, Connor M. Zackariya, Nuha Thomas, Anthony V. Langford, Jack H. Aboukhaled, Michael Thomas, Samuel J. Ansari, Aida Patel, Shivani S. Buckner, Hallie Miller, Joseph B. Annis, Christy L. Quate‐Operacz, Margaret A. Schmitz, Leslie A. Pulvirenti, Joseph J. Konopinski, Jonathan C. Kelley, Kathleen M. Hassna, Samer Nelligan, Luke G. Walsh, Mark M. |
author_facet | Bunch, Connor M. Zackariya, Nuha Thomas, Anthony V. Langford, Jack H. Aboukhaled, Michael Thomas, Samuel J. Ansari, Aida Patel, Shivani S. Buckner, Hallie Miller, Joseph B. Annis, Christy L. Quate‐Operacz, Margaret A. Schmitz, Leslie A. Pulvirenti, Joseph J. Konopinski, Jonathan C. Kelley, Kathleen M. Hassna, Samer Nelligan, Luke G. Walsh, Mark M. |
author_sort | Bunch, Connor M. |
collection | PubMed |
description | SARS‐CoV‐2 infection can manifest many rashes. However, thrombotic retiform purpura rarely occurs during COVID‐19 illness. Aggressive anti‐COVID‐19 therapy with a high‐dose steroid regimen led to rapid recovery. This immunothrombotic phenomenon likely represents a poor type 1 interferon response and complement activation on the endothelial surface in response to acute infection. |
format | Online Article Text |
id | pubmed-9795088 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | John Wiley and Sons Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-97950882022-12-30 COVID‐associated non‐vasculitic thrombotic retiform purpura of the face and extremities: A case report Bunch, Connor M. Zackariya, Nuha Thomas, Anthony V. Langford, Jack H. Aboukhaled, Michael Thomas, Samuel J. Ansari, Aida Patel, Shivani S. Buckner, Hallie Miller, Joseph B. Annis, Christy L. Quate‐Operacz, Margaret A. Schmitz, Leslie A. Pulvirenti, Joseph J. Konopinski, Jonathan C. Kelley, Kathleen M. Hassna, Samer Nelligan, Luke G. Walsh, Mark M. Clin Case Rep Case Report SARS‐CoV‐2 infection can manifest many rashes. However, thrombotic retiform purpura rarely occurs during COVID‐19 illness. Aggressive anti‐COVID‐19 therapy with a high‐dose steroid regimen led to rapid recovery. This immunothrombotic phenomenon likely represents a poor type 1 interferon response and complement activation on the endothelial surface in response to acute infection. John Wiley and Sons Inc. 2022-12-27 /pmc/articles/PMC9795088/ /pubmed/36590660 http://dx.doi.org/10.1002/ccr3.6790 Text en © 2022 The Authors. Clinical Case Reports published by John Wiley & Sons Ltd. https://creativecommons.org/licenses/by-nc/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes. |
spellingShingle | Case Report Bunch, Connor M. Zackariya, Nuha Thomas, Anthony V. Langford, Jack H. Aboukhaled, Michael Thomas, Samuel J. Ansari, Aida Patel, Shivani S. Buckner, Hallie Miller, Joseph B. Annis, Christy L. Quate‐Operacz, Margaret A. Schmitz, Leslie A. Pulvirenti, Joseph J. Konopinski, Jonathan C. Kelley, Kathleen M. Hassna, Samer Nelligan, Luke G. Walsh, Mark M. COVID‐associated non‐vasculitic thrombotic retiform purpura of the face and extremities: A case report |
title |
COVID‐associated non‐vasculitic thrombotic retiform purpura of the face and extremities: A case report |
title_full |
COVID‐associated non‐vasculitic thrombotic retiform purpura of the face and extremities: A case report |
title_fullStr |
COVID‐associated non‐vasculitic thrombotic retiform purpura of the face and extremities: A case report |
title_full_unstemmed |
COVID‐associated non‐vasculitic thrombotic retiform purpura of the face and extremities: A case report |
title_short |
COVID‐associated non‐vasculitic thrombotic retiform purpura of the face and extremities: A case report |
title_sort | covid‐associated non‐vasculitic thrombotic retiform purpura of the face and extremities: a case report |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9795088/ https://www.ncbi.nlm.nih.gov/pubmed/36590660 http://dx.doi.org/10.1002/ccr3.6790 |
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