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COVID‐associated non‐vasculitic thrombotic retiform purpura of the face and extremities: A case report

SARS‐CoV‐2 infection can manifest many rashes. However, thrombotic retiform purpura rarely occurs during COVID‐19 illness. Aggressive anti‐COVID‐19 therapy with a high‐dose steroid regimen led to rapid recovery. This immunothrombotic phenomenon likely represents a poor type 1 interferon response and...

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Autores principales: Bunch, Connor M., Zackariya, Nuha, Thomas, Anthony V., Langford, Jack H., Aboukhaled, Michael, Thomas, Samuel J., Ansari, Aida, Patel, Shivani S., Buckner, Hallie, Miller, Joseph B., Annis, Christy L., Quate‐Operacz, Margaret A., Schmitz, Leslie A., Pulvirenti, Joseph J., Konopinski, Jonathan C., Kelley, Kathleen M., Hassna, Samer, Nelligan, Luke G., Walsh, Mark M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9795088/
https://www.ncbi.nlm.nih.gov/pubmed/36590660
http://dx.doi.org/10.1002/ccr3.6790
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author Bunch, Connor M.
Zackariya, Nuha
Thomas, Anthony V.
Langford, Jack H.
Aboukhaled, Michael
Thomas, Samuel J.
Ansari, Aida
Patel, Shivani S.
Buckner, Hallie
Miller, Joseph B.
Annis, Christy L.
Quate‐Operacz, Margaret A.
Schmitz, Leslie A.
Pulvirenti, Joseph J.
Konopinski, Jonathan C.
Kelley, Kathleen M.
Hassna, Samer
Nelligan, Luke G.
Walsh, Mark M.
author_facet Bunch, Connor M.
Zackariya, Nuha
Thomas, Anthony V.
Langford, Jack H.
Aboukhaled, Michael
Thomas, Samuel J.
Ansari, Aida
Patel, Shivani S.
Buckner, Hallie
Miller, Joseph B.
Annis, Christy L.
Quate‐Operacz, Margaret A.
Schmitz, Leslie A.
Pulvirenti, Joseph J.
Konopinski, Jonathan C.
Kelley, Kathleen M.
Hassna, Samer
Nelligan, Luke G.
Walsh, Mark M.
author_sort Bunch, Connor M.
collection PubMed
description SARS‐CoV‐2 infection can manifest many rashes. However, thrombotic retiform purpura rarely occurs during COVID‐19 illness. Aggressive anti‐COVID‐19 therapy with a high‐dose steroid regimen led to rapid recovery. This immunothrombotic phenomenon likely represents a poor type 1 interferon response and complement activation on the endothelial surface in response to acute infection.
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spelling pubmed-97950882022-12-30 COVID‐associated non‐vasculitic thrombotic retiform purpura of the face and extremities: A case report Bunch, Connor M. Zackariya, Nuha Thomas, Anthony V. Langford, Jack H. Aboukhaled, Michael Thomas, Samuel J. Ansari, Aida Patel, Shivani S. Buckner, Hallie Miller, Joseph B. Annis, Christy L. Quate‐Operacz, Margaret A. Schmitz, Leslie A. Pulvirenti, Joseph J. Konopinski, Jonathan C. Kelley, Kathleen M. Hassna, Samer Nelligan, Luke G. Walsh, Mark M. Clin Case Rep Case Report SARS‐CoV‐2 infection can manifest many rashes. However, thrombotic retiform purpura rarely occurs during COVID‐19 illness. Aggressive anti‐COVID‐19 therapy with a high‐dose steroid regimen led to rapid recovery. This immunothrombotic phenomenon likely represents a poor type 1 interferon response and complement activation on the endothelial surface in response to acute infection. John Wiley and Sons Inc. 2022-12-27 /pmc/articles/PMC9795088/ /pubmed/36590660 http://dx.doi.org/10.1002/ccr3.6790 Text en © 2022 The Authors. Clinical Case Reports published by John Wiley & Sons Ltd. https://creativecommons.org/licenses/by-nc/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.
spellingShingle Case Report
Bunch, Connor M.
Zackariya, Nuha
Thomas, Anthony V.
Langford, Jack H.
Aboukhaled, Michael
Thomas, Samuel J.
Ansari, Aida
Patel, Shivani S.
Buckner, Hallie
Miller, Joseph B.
Annis, Christy L.
Quate‐Operacz, Margaret A.
Schmitz, Leslie A.
Pulvirenti, Joseph J.
Konopinski, Jonathan C.
Kelley, Kathleen M.
Hassna, Samer
Nelligan, Luke G.
Walsh, Mark M.
COVID‐associated non‐vasculitic thrombotic retiform purpura of the face and extremities: A case report
title COVID‐associated non‐vasculitic thrombotic retiform purpura of the face and extremities: A case report
title_full COVID‐associated non‐vasculitic thrombotic retiform purpura of the face and extremities: A case report
title_fullStr COVID‐associated non‐vasculitic thrombotic retiform purpura of the face and extremities: A case report
title_full_unstemmed COVID‐associated non‐vasculitic thrombotic retiform purpura of the face and extremities: A case report
title_short COVID‐associated non‐vasculitic thrombotic retiform purpura of the face and extremities: A case report
title_sort covid‐associated non‐vasculitic thrombotic retiform purpura of the face and extremities: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9795088/
https://www.ncbi.nlm.nih.gov/pubmed/36590660
http://dx.doi.org/10.1002/ccr3.6790
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