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A case of severe increase of liver enzymes in a ATTRv patient after one year of inotersen treatment
BACKGROUND: Inotersen is an antisense oligonucleotide used to treat hereditary transthyretin amyloidosis (ATTRv). The most common drug-related adverse effects (AEs) include thrombocytopenia and glomerulonephritis. Hepatic damage is rare, but liver enzyme monitoring is mandatory. CASE REPORT: A 70-ye...
Autores principales: | Severi, Daniele, Palumbo, Giovanni, Spina, Emanuele, Iovino, Aniello, Nolano, Maria, Manganelli, Fiore, Tozza, Stefano |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9795110/ https://www.ncbi.nlm.nih.gov/pubmed/36576645 http://dx.doi.org/10.1007/s10072-022-06568-w |
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