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Autoimmune Hepatitis Leading to Liver Cirrhosis: A Case Report

Autoimmune hepatitis is a rare form of chronic liver inflammation that begins as acute hepatitis and progresses to chronic liver disease. It presents with varied clinical features from acute hepatitis to chronic liver diseases like chronic viral hepatitis and alcoholic liver disease, making it diffi...

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Autores principales: Shrestha, Moon, Subedi, Sudip Chandra, Shah, Sangam, Acharya, Jeny, Regmi, Milan, Mehta, Neha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Journal of the Nepal Medical Association 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9795117/
https://www.ncbi.nlm.nih.gov/pubmed/36705108
http://dx.doi.org/10.31729/jnma.7808
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author Shrestha, Moon
Subedi, Sudip Chandra
Shah, Sangam
Acharya, Jeny
Regmi, Milan
Mehta, Neha
author_facet Shrestha, Moon
Subedi, Sudip Chandra
Shah, Sangam
Acharya, Jeny
Regmi, Milan
Mehta, Neha
author_sort Shrestha, Moon
collection PubMed
description Autoimmune hepatitis is a rare form of chronic liver inflammation that begins as acute hepatitis and progresses to chronic liver disease. It presents with varied clinical features from acute hepatitis to chronic liver diseases like chronic viral hepatitis and alcoholic liver disease, making it difficult to diagnose in the absence of a high index of suspicion and adequate laboratory support. Autoimmune hepatitis is divided into two categories autoimmune hepatitis-1 and autoimmune hepatitis-2 based on the antibodies involved. We discuss the case of a 37-year-old woman who developed autoimmune hepatitis-1, with swelling and epigastric pain. These symptoms later progressed to liver cirrhosis leading to the death of the patient. Autoimmune hepatitis is extremely sensitive to immunosuppressive medication, it is necessary to maintain a high suspicion index for the disease because a prompt diagnosis can be an integral step toward a better prognosis of the disease.
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spelling pubmed-97951172023-01-04 Autoimmune Hepatitis Leading to Liver Cirrhosis: A Case Report Shrestha, Moon Subedi, Sudip Chandra Shah, Sangam Acharya, Jeny Regmi, Milan Mehta, Neha JNMA J Nepal Med Assoc Case Report Autoimmune hepatitis is a rare form of chronic liver inflammation that begins as acute hepatitis and progresses to chronic liver disease. It presents with varied clinical features from acute hepatitis to chronic liver diseases like chronic viral hepatitis and alcoholic liver disease, making it difficult to diagnose in the absence of a high index of suspicion and adequate laboratory support. Autoimmune hepatitis is divided into two categories autoimmune hepatitis-1 and autoimmune hepatitis-2 based on the antibodies involved. We discuss the case of a 37-year-old woman who developed autoimmune hepatitis-1, with swelling and epigastric pain. These symptoms later progressed to liver cirrhosis leading to the death of the patient. Autoimmune hepatitis is extremely sensitive to immunosuppressive medication, it is necessary to maintain a high suspicion index for the disease because a prompt diagnosis can be an integral step toward a better prognosis of the disease. Journal of the Nepal Medical Association 2022-12 2022-12-31 /pmc/articles/PMC9795117/ /pubmed/36705108 http://dx.doi.org/10.31729/jnma.7808 Text en © The Author(s) 2018. https://creativecommons.org/licenses/by/4.0/This is an Open-Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Shrestha, Moon
Subedi, Sudip Chandra
Shah, Sangam
Acharya, Jeny
Regmi, Milan
Mehta, Neha
Autoimmune Hepatitis Leading to Liver Cirrhosis: A Case Report
title Autoimmune Hepatitis Leading to Liver Cirrhosis: A Case Report
title_full Autoimmune Hepatitis Leading to Liver Cirrhosis: A Case Report
title_fullStr Autoimmune Hepatitis Leading to Liver Cirrhosis: A Case Report
title_full_unstemmed Autoimmune Hepatitis Leading to Liver Cirrhosis: A Case Report
title_short Autoimmune Hepatitis Leading to Liver Cirrhosis: A Case Report
title_sort autoimmune hepatitis leading to liver cirrhosis: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9795117/
https://www.ncbi.nlm.nih.gov/pubmed/36705108
http://dx.doi.org/10.31729/jnma.7808
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