An immunocompetent rectal cancer model to study radiation therapy

We describe a mouse model of rectal cancer (RC) involving rapid tumor organoid engraftment via orthotopic transplantation in an immunocompetent setting. This approach uses simple mechanical disruption to allow engraftment, avoiding the use of dextran sulfate sodium. The resulting RC tumors invaded f...

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Detalles Bibliográficos
Autores principales: Kim, Jin K., Wu, Chao, Del Latto, Michael, Gao, Yajing, Choi, Seo-Hyun, Kierstead, Maria, Gabriel Sauvé, Charles-Etienne, Firat, Canan, Perez, Almudena Chaves, Sillanpaa, Jussi, Chen, Chin-Tung, Lawrence, Kayla E., Paty, Philip B., Barriga, Francisco M., Wilkinson, John E., Shia, Jinru, Sawyers, Charles L., Lowe, Scott W., García-Aguilar, Julio, Romesser, Paul B., Smith, J. Joshua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9795330/
https://www.ncbi.nlm.nih.gov/pubmed/36590695
http://dx.doi.org/10.1016/j.crmeth.2022.100353

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9795330/
https://www.ncbi.nlm.nih.gov/pubmed/36590695
http://dx.doi.org/10.1016/j.crmeth.2022.100353

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