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Doxycycline hyclate stimulates inducible nitric oxide synthase and arginase imbalance, potentiating inflammatory and oxidative lung damage in schistosomiasis

BACKGROUND: We investigated the relationship between inducible nitric oxide synthase (iNOS) and arginase pathways, cytokines, macrophages, oxidative damage and lung granulomatous inflammation in S. mansoni-infected and doxycycline-treated mice. METHODS: Swiss mice were randomized in four groups: (i)...

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Detalles Bibliográficos
Autores principales:	Souza, Matheus Augusto, Gonçalves-Santos, Elda, Gonçalves, Reggiani V., Santos, Eliziária C., Campos, Camila C., Marques, Marcos J., Souza, Raquel L.M., Novaes, Rômulo D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Chang Gung University 2022
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9795368/ https://www.ncbi.nlm.nih.gov/pubmed/34971826 http://dx.doi.org/10.1016/j.bj.2021.12.007

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