RosettaDDGPrediction for high‐throughput mutational scans: From stability to binding

Reliable prediction of free energy changes upon amino acid substitutions (ΔΔGs) is crucial to investigate their impact on protein stability and protein–protein interaction. Advances in experimental mutational scans allow high‐throughput studies thanks to multiplex techniques. On the other hand, geno...

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Detalles Bibliográficos
Autores principales: Sora, Valentina, Laspiur, Adrian Otamendi, Degn, Kristine, Arnaudi, Matteo, Utichi, Mattia, Beltrame, Ludovica, De Menezes, Dayana, Orlandi, Matteo, Stoltze, Ulrik Kristoffer, Rigina, Olga, Sackett, Peter Wad, Wadt, Karin, Schmiegelow, Kjeld, Tiberti, Matteo, Papaleo, Elena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2023
Materias:
Tools for Protein Science
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9795540/
https://www.ncbi.nlm.nih.gov/pubmed/36461907
http://dx.doi.org/10.1002/pro.4527

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