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Force-Field-Dependent DNA Breathing Dynamics: A Case Study of Hoogsteen Base Pairing in A6-DNA

[Image: see text] The Hoogsteen (HG) base pairing conformation, commonly observed in damaged and mutated DNA helices, facilitates DNA repair and DNA recognition. The free energy difference between HG and Watson–Crick (WC) base pairs has been computed in previous studies. However, the mechanism of th...

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Detalles Bibliográficos
Autores principales:	Stone, Sharon Emily, Ray, Dhiman, Andricioaei, Ioan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2022
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9795553/ https://www.ncbi.nlm.nih.gov/pubmed/36049242 http://dx.doi.org/10.1021/acs.jcim.2c00519

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