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Standard Binding Free Energy and Membrane Desorption Mechanism for a Phospholipase C
[Image: see text] Peripheral membrane proteins (PMPs) bind temporarily to cellular membranes and play important roles in signaling, lipid metabolism, and membrane trafficking. Obtaining accurate membrane-PMP affinities using experimental techniques is more challenging than for protein–ligand affinit...
Autores principales: | Moutoussamy, Emmanuel E., Khan, Hanif M., Roberts, Mary F., Gershenson, Anne, Chipot, Christophe, Reuter, Nathalie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9795555/ https://www.ncbi.nlm.nih.gov/pubmed/35343689 http://dx.doi.org/10.1021/acs.jcim.1c01543 |
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