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Standard Binding Free Energy and Membrane Desorption Mechanism for a Phospholipase C

[Image: see text] Peripheral membrane proteins (PMPs) bind temporarily to cellular membranes and play important roles in signaling, lipid metabolism, and membrane trafficking. Obtaining accurate membrane-PMP affinities using experimental techniques is more challenging than for protein–ligand affinit...

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Detalles Bibliográficos
Autores principales: Moutoussamy, Emmanuel E., Khan, Hanif M., Roberts, Mary F., Gershenson, Anne, Chipot, Christophe, Reuter, Nathalie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9795555/
https://www.ncbi.nlm.nih.gov/pubmed/35343689
http://dx.doi.org/10.1021/acs.jcim.1c01543

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