Cargando…
External control arm analysis: an evaluation of propensity score approaches, G-computation, and doubly debiased machine learning
BACKGROUND: An external control arm is a cohort of control patients that are collected from data external to a single-arm trial. To provide an unbiased estimation of efficacy, the clinical profiles of patients from single and external arms should be aligned, typically using propensity score approach...
Autores principales: | , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9795588/ https://www.ncbi.nlm.nih.gov/pubmed/36577946 http://dx.doi.org/10.1186/s12874-022-01799-z |