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External control arm analysis: an evaluation of propensity score approaches, G-computation, and doubly debiased machine learning

BACKGROUND: An external control arm is a cohort of control patients that are collected from data external to a single-arm trial. To provide an unbiased estimation of efficacy, the clinical profiles of patients from single and external arms should be aligned, typically using propensity score approach...

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Detalles Bibliográficos
Autores principales:	Loiseau, Nicolas, Trichelair, Paul, He, Maxime, Andreux, Mathieu, Zaslavskiy, Mikhail, Wainrib, Gilles, Blum, Michael G. B.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9795588/ https://www.ncbi.nlm.nih.gov/pubmed/36577946 http://dx.doi.org/10.1186/s12874-022-01799-z

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