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Effect of glucose depletion and fructose administration during chondrogenic commitment in human bone marrow-derived stem cells
BACKGROUND: Bone marrow mesenchymal stromal cells (BMSCs) are promising for therapeutic use in cartilage repair, because of their capacity to differentiate into chondrocytes. Often, in vitro differentiation protocols employ the use of high amount of glucose, which does not reflect cartilage physiolo...
Autores principales: | Zuncheddu, Daniele, Della Bella, Elena, Petta, Dalila, Bärtschi, Cecilia, Häckel, Sonja, Deml, Moritz C., Stoddart, Martin J., Grad, Sibylle, Basoli, Valentina |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9795608/ https://www.ncbi.nlm.nih.gov/pubmed/36575539 http://dx.doi.org/10.1186/s13287-022-03214-2 |
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