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A drug delivery system constructed by a fusion peptide capturing exosomes targets to titanium implants accurately resulting the enhancement of osseointegration peri-implant

BACKGROUND: Exosomes derived from bone marrow mesenchymal stem cells (BMSC-exos) have been shown triggering osteogenic differentiation and mineralization of MSCs, but exosomes administered via bolus injections are rapidly sequestered and cleared. Therefore, we considered the implant as a new organ o...

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Detalles Bibliográficos
Autores principales: Li, Xuewen, Liu, Zihao, Xu, Shendan, Ma, Xinying, Zhao, Zhezhe, Hu, Han, Deng, Jiayin, Peng, Cheng, Wang, Yonglan, Ma, Shiqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9795642/
https://www.ncbi.nlm.nih.gov/pubmed/36575503
http://dx.doi.org/10.1186/s40824-022-00331-0