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A drug delivery system constructed by a fusion peptide capturing exosomes targets to titanium implants accurately resulting the enhancement of osseointegration peri-implant
BACKGROUND: Exosomes derived from bone marrow mesenchymal stem cells (BMSC-exos) have been shown triggering osteogenic differentiation and mineralization of MSCs, but exosomes administered via bolus injections are rapidly sequestered and cleared. Therefore, we considered the implant as a new organ o...
Autores principales: | Li, Xuewen, Liu, Zihao, Xu, Shendan, Ma, Xinying, Zhao, Zhezhe, Hu, Han, Deng, Jiayin, Peng, Cheng, Wang, Yonglan, Ma, Shiqing |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9795642/ https://www.ncbi.nlm.nih.gov/pubmed/36575503 http://dx.doi.org/10.1186/s40824-022-00331-0 |
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