Global neuropathologic severity of Alzheimer’s disease and locus coeruleus vulnerability influences plasma phosphorylated tau levels

BACKGROUND: Advances in ultrasensitive detection of phosphorylated tau (p-tau) in plasma has enabled the use of blood tests to measure Alzheimer’s disease (AD) biomarker changes. Examination of postmortem brains of participants with antemortem plasma p-tau levels remains critical to understanding co...

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Detalles Bibliográficos
Autores principales: Murray, Melissa E., Moloney, Christina M., Kouri, Naomi, Syrjanen, Jeremy A., Matchett, Billie J., Rothberg, Darren M., Tranovich, Jessica F., Sirmans, Tiffany N. Hicks, Wiste, Heather J., Boon, Baayla D. C., Nguyen, Aivi T., Reichard, R. Ross, Dickson, Dennis W., Lowe, Val J., Dage, Jeffrey L., Petersen, Ronald C., Jack, Clifford R., Knopman, David S., Vemuri, Prashanthi, Graff-Radford, Jonathan, Mielke, Michelle M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9795667/
https://www.ncbi.nlm.nih.gov/pubmed/36575455
http://dx.doi.org/10.1186/s13024-022-00578-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9795667/
https://www.ncbi.nlm.nih.gov/pubmed/36575455
http://dx.doi.org/10.1186/s13024-022-00578-0

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