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Kampo formula hochu-ekki-to (Bu-Zhong-Yi-Qi-Tang, TJ-41) ameliorates muscle atrophy by modulating atrogenes and AMPK in vivo and in vitro

BACKGROUND: Muscle disuse results in loss of skeletal muscle mass and function. Hochu-ekki-to (TJ-41; Bu-Zhong-Yi-Qi-Tang in Chinese) is an herbal medicinal formulation used to treat patients with frailty, fatigue and appetite loss. It has been suggested that two atrogenes, atrogin-1 and muscle Ring...

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Detalles Bibliográficos
Autores principales:	Yakabe, Mitsutaka, Hosoi, Tatsuya, Sasakawa, Hiroko, Akishita, Masahiro, Ogawa, Sumito
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9795672/ https://www.ncbi.nlm.nih.gov/pubmed/36578084 http://dx.doi.org/10.1186/s12906-022-03812-w

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