Nebulization of risedronate alleviates airway obstruction and inflammation of chronic obstructive pulmonary diseases via suppressing prenylation-dependent RAS/ERK/NF-κB and RhoA/ROCK1/MLCP signaling

BACKGROUND: Chronic obstructive pulmonary disease (COPD) is a progressive disorder that causes airway obstruction and lung inflammation. The first-line treatment of COPD is the bronchodilators of β2-agonists and antimuscarinic drugs, which can help control the airway obstruction, but the long-term u...

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Detalles Bibliográficos
Autores principales: Liu, Di, Xu, Wen, Tang, Yuan, Cao, Jingxue, Chen, Ran, Wu, Dingwei, Chen, Hongpeng, Su, Bo, Xu, Jinfu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9795678/
https://www.ncbi.nlm.nih.gov/pubmed/36575527
http://dx.doi.org/10.1186/s12931-022-02274-5

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