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Facet overhang: A novel parameter in the pathophysiology of multifidus muscle atrophy
The relationship between degenerative zygapophysial joint (facet) arthropathy and multifidus muscle atrophy has not been rigorously evaluated. The purpose of this study was to determine if specific morphological features of degenerative facet arthropathy are correlated with multifidus muscle atrophy...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons, Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9795881/ https://www.ncbi.nlm.nih.gov/pubmed/35701879 http://dx.doi.org/10.1002/ca.23923 |
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author | Chua, Michelle Salame, Khalil Khashan, Morsi Ofir, Dror Hochberg, Uri Ankory, Ran Lidar, Zvi Regev, Gilad J. |
author_facet | Chua, Michelle Salame, Khalil Khashan, Morsi Ofir, Dror Hochberg, Uri Ankory, Ran Lidar, Zvi Regev, Gilad J. |
author_sort | Chua, Michelle |
collection | PubMed |
description | The relationship between degenerative zygapophysial joint (facet) arthropathy and multifidus muscle atrophy has not been rigorously evaluated. The purpose of this study was to determine if specific morphological features of degenerative facet arthropathy are correlated with multifidus muscle atrophy. We retrospectively reviewed medical records and imaging studies of patients with lumbar spinal stenosis. Facet overhang, bridging osteophyte formation, facet effusion, and facet angles were evaluated by univariable and multivariable regression to identify independent associations with deep and superficial parts of the multifidus total cross‐sectional area (tCSA), functional cross‐sectional area (fnCSA), and fatty infiltration (FI). Facet overhang was classified as severe in 50 females (53.2%) versus 56 males (36.9%) (p = 0.030). Severity of facet overhang and female sex were independently associated with smaller deep part of the multifidus tCSA and fnCSA as well as higher FI, reflecting greater atrophy of the deep region compared to total muscle mass. In comparison, severe facet overhang (p < 0.001; OR = 3.47, 95% CI = 2.13–5.66) and female sex (p < 0.001; OR = 4.19, 95% CI = 2.58–6.79) were independently associated only with higher superficial part of the multifidus FI, reflecting muscle steatosis without significant lean muscle atrophy. In patients with degenerative lumbar spinal stenosis, facet overhang is an independent risk factor for deep part of the multifidus atrophy. Bridging osteophyte formation, facet effusion, and facet angles were not independently associated with deep part of the multifidus atrophy. |
format | Online Article Text |
id | pubmed-9795881 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | John Wiley & Sons, Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-97958812022-12-28 Facet overhang: A novel parameter in the pathophysiology of multifidus muscle atrophy Chua, Michelle Salame, Khalil Khashan, Morsi Ofir, Dror Hochberg, Uri Ankory, Ran Lidar, Zvi Regev, Gilad J. Clin Anat Communications The relationship between degenerative zygapophysial joint (facet) arthropathy and multifidus muscle atrophy has not been rigorously evaluated. The purpose of this study was to determine if specific morphological features of degenerative facet arthropathy are correlated with multifidus muscle atrophy. We retrospectively reviewed medical records and imaging studies of patients with lumbar spinal stenosis. Facet overhang, bridging osteophyte formation, facet effusion, and facet angles were evaluated by univariable and multivariable regression to identify independent associations with deep and superficial parts of the multifidus total cross‐sectional area (tCSA), functional cross‐sectional area (fnCSA), and fatty infiltration (FI). Facet overhang was classified as severe in 50 females (53.2%) versus 56 males (36.9%) (p = 0.030). Severity of facet overhang and female sex were independently associated with smaller deep part of the multifidus tCSA and fnCSA as well as higher FI, reflecting greater atrophy of the deep region compared to total muscle mass. In comparison, severe facet overhang (p < 0.001; OR = 3.47, 95% CI = 2.13–5.66) and female sex (p < 0.001; OR = 4.19, 95% CI = 2.58–6.79) were independently associated only with higher superficial part of the multifidus FI, reflecting muscle steatosis without significant lean muscle atrophy. In patients with degenerative lumbar spinal stenosis, facet overhang is an independent risk factor for deep part of the multifidus atrophy. Bridging osteophyte formation, facet effusion, and facet angles were not independently associated with deep part of the multifidus atrophy. John Wiley & Sons, Inc. 2022-06-23 2022-11 /pmc/articles/PMC9795881/ /pubmed/35701879 http://dx.doi.org/10.1002/ca.23923 Text en © 2022 The Authors. Clinical Anatomy published by Wiley Periodicals LLC on behalf of American Association of Clinical Anatomists and British Association of Clinical Anatomists. https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Communications Chua, Michelle Salame, Khalil Khashan, Morsi Ofir, Dror Hochberg, Uri Ankory, Ran Lidar, Zvi Regev, Gilad J. Facet overhang: A novel parameter in the pathophysiology of multifidus muscle atrophy |
title | Facet overhang: A novel parameter in the pathophysiology of multifidus muscle atrophy |
title_full | Facet overhang: A novel parameter in the pathophysiology of multifidus muscle atrophy |
title_fullStr | Facet overhang: A novel parameter in the pathophysiology of multifidus muscle atrophy |
title_full_unstemmed | Facet overhang: A novel parameter in the pathophysiology of multifidus muscle atrophy |
title_short | Facet overhang: A novel parameter in the pathophysiology of multifidus muscle atrophy |
title_sort | facet overhang: a novel parameter in the pathophysiology of multifidus muscle atrophy |
topic | Communications |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9795881/ https://www.ncbi.nlm.nih.gov/pubmed/35701879 http://dx.doi.org/10.1002/ca.23923 |
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