In vivo and in vitro characterization of GL0034, a novel long‐acting glucagon‐like peptide‐1 receptor agonist

AIMS: To describe the in vitro characteristics and antidiabetic in vivo efficacy of the novel glucagon‐like peptide‐1 receptor agonist (GLP‐1RA) GL0034. MATERIALS AND METHODS: Glucagon‐like peptide‐1 receptor (GLP‐1R) kinetic binding parameters, cyclic adenosine monophosphate (cAMP) signalling, endo...

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Detalles Bibliográficos
Autores principales: Jones, Ben, Burade, Vinod, Akalestou, Elina, Manchanda, Yusman, Ramchunder, Zenouska, Carrat, Gaëlle, Nguyen‐Tu, Marie‐Sophie, Marchetti, Piero, Piemonti, Lorenzo, Leclerc, Isabelle, Thennati, Rajamannar, Vilsboll, Tina, Thorens, Bernard, Tomas, Alejandra, Rutter, Guy A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2022
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9796023/
https://www.ncbi.nlm.nih.gov/pubmed/35676825
http://dx.doi.org/10.1111/dom.14794

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