SARS-CoV-2 Omicron BA.5 Infections in Vaccinated Persons, Rural Uganda

We describe a cluster of COVID-19 breakthrough infections after vaccination in Kyamulibwa, Kalungu District, Uganda. All but 1 infection were from SARS-CoV-2 Omicron strain BA.5.2.1. We identified 6 distinct genotypes by genome sequencing. Infections were mild, suggesting vaccination is not protecti...

Descripción completa

Detalles Bibliográficos
Autores principales: Mugisha, Joseph, Mpairwe, Bernard, Newton, Robert, Cotten, Matthew, Phan, My V.T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2023
Materias:
Research Letter
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9796194/
https://www.ncbi.nlm.nih.gov/pubmed/36529453
http://dx.doi.org/10.3201/eid2901.220981
_version_ 1784860427365122048
author Mugisha, Joseph
Mpairwe, Bernard
Newton, Robert
Cotten, Matthew
Phan, My V.T.
author_facet Mugisha, Joseph
Mpairwe, Bernard
Newton, Robert
Cotten, Matthew
Phan, My V.T.
author_sort Mugisha, Joseph
collection PubMed
description We describe a cluster of COVID-19 breakthrough infections after vaccination in Kyamulibwa, Kalungu District, Uganda. All but 1 infection were from SARS-CoV-2 Omicron strain BA.5.2.1. We identified 6 distinct genotypes by genome sequencing. Infections were mild, suggesting vaccination is not protective against infection but may limit disease severity.
format Online
Article
Text
id pubmed-9796194
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher Centers for Disease Control and Prevention
record_format MEDLINE/PubMed
spelling pubmed-97961942023-01-09 SARS-CoV-2 Omicron BA.5 Infections in Vaccinated Persons, Rural Uganda Mugisha, Joseph Mpairwe, Bernard Newton, Robert Cotten, Matthew Phan, My V.T. Emerg Infect Dis Research Letter We describe a cluster of COVID-19 breakthrough infections after vaccination in Kyamulibwa, Kalungu District, Uganda. All but 1 infection were from SARS-CoV-2 Omicron strain BA.5.2.1. We identified 6 distinct genotypes by genome sequencing. Infections were mild, suggesting vaccination is not protective against infection but may limit disease severity. Centers for Disease Control and Prevention 2023-01 /pmc/articles/PMC9796194/ /pubmed/36529453 http://dx.doi.org/10.3201/eid2901.220981 Text en https://creativecommons.org/licenses/by/4.0/Emerging Infectious Diseases is a publication of the U.S. Government. This publication is in the public domain and is therefore without copyright. All text from this work may be reprinted freely. Use of these materials should be properly cited.
spellingShingle Research Letter
Mugisha, Joseph
Mpairwe, Bernard
Newton, Robert
Cotten, Matthew
Phan, My V.T.
SARS-CoV-2 Omicron BA.5 Infections in Vaccinated Persons, Rural Uganda
title SARS-CoV-2 Omicron BA.5 Infections in Vaccinated Persons, Rural Uganda
title_full SARS-CoV-2 Omicron BA.5 Infections in Vaccinated Persons, Rural Uganda
title_fullStr SARS-CoV-2 Omicron BA.5 Infections in Vaccinated Persons, Rural Uganda
title_full_unstemmed SARS-CoV-2 Omicron BA.5 Infections in Vaccinated Persons, Rural Uganda
title_short SARS-CoV-2 Omicron BA.5 Infections in Vaccinated Persons, Rural Uganda
title_sort sars-cov-2 omicron ba.5 infections in vaccinated persons, rural uganda
topic Research Letter
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9796194/
https://www.ncbi.nlm.nih.gov/pubmed/36529453
http://dx.doi.org/10.3201/eid2901.220981
work_keys_str_mv AT mugishajoseph sarscov2omicronba5infectionsinvaccinatedpersonsruraluganda
AT mpairwebernard sarscov2omicronba5infectionsinvaccinatedpersonsruraluganda
AT newtonrobert sarscov2omicronba5infectionsinvaccinatedpersonsruraluganda
AT cottenmatthew sarscov2omicronba5infectionsinvaccinatedpersonsruraluganda
AT phanmyvt sarscov2omicronba5infectionsinvaccinatedpersonsruraluganda

Ejemplares similares