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Plasmodium falciparum pfhrp2 and pfhrp3 Gene Deletions in Malaria-Hyperendemic Region, South Sudan
Pfhrp2 and pfhrp3 gene deletions threaten the use of Plasmodium falciparum malaria rapid diagnostic tests globally. In South Sudan, deletion frequencies were 15.6% for pfhrp2, 20.0% for pfhrp3, and 7.5% for double deletions. Deletions were approximately twice as prevalent in monoclonal infections th...
| Autores principales: | , , , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Centers for Disease Control and Prevention
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9796199/ https://www.ncbi.nlm.nih.gov/pubmed/36573593 http://dx.doi.org/10.3201/eid2901.220775 |
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| author | Molina-de la Fuente, Irene Benito, María José Sagrado Flevaud, Laurence Ousley, Janet Pasquale, Harriet Akello Julla, Ahmed Abdi, Abdirashid M. Chol, Buai Tut Abubakr, Bakri Benito, Agustín Casademont, Cristian Nanclares, Carolina Berzosa, Pedro |
| author_facet | Molina-de la Fuente, Irene Benito, María José Sagrado Flevaud, Laurence Ousley, Janet Pasquale, Harriet Akello Julla, Ahmed Abdi, Abdirashid M. Chol, Buai Tut Abubakr, Bakri Benito, Agustín Casademont, Cristian Nanclares, Carolina Berzosa, Pedro |
| author_sort | Molina-de la Fuente, Irene |
| collection | PubMed |
| description | Pfhrp2 and pfhrp3 gene deletions threaten the use of Plasmodium falciparum malaria rapid diagnostic tests globally. In South Sudan, deletion frequencies were 15.6% for pfhrp2, 20.0% for pfhrp3, and 7.5% for double deletions. Deletions were approximately twice as prevalent in monoclonal infections than in polyclonal infections. |
| format | Online Article Text |
| id | pubmed-9796199 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2023 |
| publisher | Centers for Disease Control and Prevention |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-97961992023-01-09 Plasmodium falciparum pfhrp2 and pfhrp3 Gene Deletions in Malaria-Hyperendemic Region, South Sudan Molina-de la Fuente, Irene Benito, María José Sagrado Flevaud, Laurence Ousley, Janet Pasquale, Harriet Akello Julla, Ahmed Abdi, Abdirashid M. Chol, Buai Tut Abubakr, Bakri Benito, Agustín Casademont, Cristian Nanclares, Carolina Berzosa, Pedro Emerg Infect Dis Dispatch Pfhrp2 and pfhrp3 gene deletions threaten the use of Plasmodium falciparum malaria rapid diagnostic tests globally. In South Sudan, deletion frequencies were 15.6% for pfhrp2, 20.0% for pfhrp3, and 7.5% for double deletions. Deletions were approximately twice as prevalent in monoclonal infections than in polyclonal infections. Centers for Disease Control and Prevention 2023-01 /pmc/articles/PMC9796199/ /pubmed/36573593 http://dx.doi.org/10.3201/eid2901.220775 Text en https://creativecommons.org/licenses/by/4.0/Emerging Infectious Diseases is a publication of the U.S. Government. This publication is in the public domain and is therefore without copyright. All text from this work may be reprinted freely. Use of these materials should be properly cited. |
| spellingShingle | Dispatch Molina-de la Fuente, Irene Benito, María José Sagrado Flevaud, Laurence Ousley, Janet Pasquale, Harriet Akello Julla, Ahmed Abdi, Abdirashid M. Chol, Buai Tut Abubakr, Bakri Benito, Agustín Casademont, Cristian Nanclares, Carolina Berzosa, Pedro Plasmodium falciparum pfhrp2 and pfhrp3 Gene Deletions in Malaria-Hyperendemic Region, South Sudan |
| title | Plasmodium falciparum pfhrp2 and pfhrp3 Gene Deletions in Malaria-Hyperendemic Region, South Sudan |
| title_full | Plasmodium falciparum pfhrp2 and pfhrp3 Gene Deletions in Malaria-Hyperendemic Region, South Sudan |
| title_fullStr | Plasmodium falciparum pfhrp2 and pfhrp3 Gene Deletions in Malaria-Hyperendemic Region, South Sudan |
| title_full_unstemmed | Plasmodium falciparum pfhrp2 and pfhrp3 Gene Deletions in Malaria-Hyperendemic Region, South Sudan |
| title_short | Plasmodium falciparum pfhrp2 and pfhrp3 Gene Deletions in Malaria-Hyperendemic Region, South Sudan |
| title_sort | plasmodium falciparum pfhrp2 and pfhrp3 gene deletions in malaria-hyperendemic region, south sudan |
| topic | Dispatch |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9796199/ https://www.ncbi.nlm.nih.gov/pubmed/36573593 http://dx.doi.org/10.3201/eid2901.220775 |
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