Genomic Microevolution of Vibrio cholerae O1, Lake Tanganyika Basin, Africa

Africa’s Lake Tanganyika basin is a cholera hotspot. During 2001–2020, Vibrio cholerae O1 isolates obtained from the Democratic Republic of the Congo side of the lake belonged to 2 of the 5 clades of the AFR10 sublineage. One clade became predominant after acquiring a parC mutation that decreased su...

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Detalles Bibliográficos
Autores principales: Hounmanou, Yaovi M.G., Njamkepo, Elisabeth, Rauzier, Jean, Gallandat, Karin, Jeandron, Aurélie, Kamwiziku, Guyguy, Porten, Klaudia, Luquero, Francisco, Abedi, Aaron Aruna, Rumedeka, Baron Bashige, Miwanda, Berthe, Michael, Martin, Okitayemba, Placide Welo, Saidi, Jaime Mufitini, Piarroux, Renaud, Weill, François-Xavier, Dalsgaard, Anders, Quilici, Marie-Laure
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2023
Materias:
Dispatch
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9796204/
https://www.ncbi.nlm.nih.gov/pubmed/36573719
http://dx.doi.org/10.3201/eid2901.220641
Descripción
Sumario:Africa’s Lake Tanganyika basin is a cholera hotspot. During 2001–2020, Vibrio cholerae O1 isolates obtained from the Democratic Republic of the Congo side of the lake belonged to 2 of the 5 clades of the AFR10 sublineage. One clade became predominant after acquiring a parC mutation that decreased susceptibility to ciprofloxacin.

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