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A multi‐hit hypothesis for an APOE4‐dependent pathophysiological state

The APOE gene encoding the Apolipoprotein E protein is the single most significant genetic risk factor for late‐onset Alzheimer's disease. The APOE4 genotype confers a significantly increased risk relative to the other two common genotypes APOE3 and APOE2. Intriguingly, APOE4 has been associate...

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Detalles Bibliográficos
Autores principales:	Steele, Oliver George, Stuart, Alexander Cameron, Minkley, Lucy, Shaw, Kira, Bonnar, Orla, Anderle, Silvia, Penn, Andrew Charles, Rusted, Jennifer, Serpell, Louise, Hall, Catherine, King, Sarah
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2022
Materias:	Special Issue Reviews
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9796338/ https://www.ncbi.nlm.nih.gov/pubmed/35510513 http://dx.doi.org/10.1111/ejn.15685

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