Cargando…

A Versatile Chemoenzymatic Nanoreactor that Mimics NAD(P)H Oxidase for the In Situ Regeneration of Cofactors

Herein, we report a multifunctional chemoenzymatic nanoreactor (NanoNOx) for the glucose‐controlled regeneration of natural and artificial nicotinamide cofactors. NanoNOx are built of glucose oxidase‐polymer hybrids that assemble in the presence of an organometallic catalyst: hemin. The design of th...

Descripción completa

Detalles Bibliográficos
Autores principales:	Rodriguez‐Abetxuko, Andoni, Reifs, Antonio, Sánchez‐deAlcázar, Daniel, Beloqui, Ana
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2022
Materias:	Communications
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9796410/ https://www.ncbi.nlm.nih.gov/pubmed/35762738 http://dx.doi.org/10.1002/anie.202206926

Ejemplares similares

Metal–Organic Enzyme Nanogels as Nanointegrated Self-Reporting Chemobiosensors
por: Sánchez-deAlcázar, Daniel, et al.
Publicado: (2022)

Tunable Polymeric Scaffolds for Enzyme Immobilization
por: Rodriguez-Abetxuko, Andoni, et al.
Publicado: (2020)

Facile chemoenzymatic synthesis of a novel stable mimic of NAD(+)
por: Dai, Zhefu, et al.
Publicado: (2018)

Cofactor Specificity Engineering of Streptococcus mutans NADH Oxidase 2 for NAD(P)(+) Regeneration in Biocatalytic Oxidations
por: Petschacher, Barbara, et al.
Publicado: (2014)

A versatile nanoreactor for complementary in situ X-ray and electron microscopy studies in catalysis and materials science
por: Fam, Yakub, et al.
Publicado: (2019)

Cell Membrane-Based Nanoreactor To Mimic the Bio-Compartmentalization Strategy of a Cell
por: Balasubramanian, Vimalkumar, et al.
Publicado: (2018)

Evidence that the nadA motif is a bacterial riboswitch for the ubiquitous enzyme cofactor NAD(+)
por: Malkowski, Sarah N., et al.
Publicado: (2019)

A second riboswitch class for the enzyme cofactor NAD(+)
por: Panchapakesan, Shanker S.S., et al.
Publicado: (2021)

Functionalised Cofactor Mimics for Interactome Discovery and Beyond
por: Wilkinson, Isabel V. L., et al.
Publicado: (2022)

Harnessing galactose oxidase in the development of a chemoenzymatic platform for glycoconjugate vaccine design
por: Duke, Jeremy A., et al.
Publicado: (2021)

Mycofactocin-associated mycobacterial dehydrogenases with non-exchangeable NAD cofactors
por: Haft, Daniel H., et al.
Publicado: (2017)

Mimic of the Cellular Antioxidant Defense System for a Sustainable Regeneration of Nicotinamide Adenine Dinucleotide (NAD)
por: Jo, Seong-Min, et al.
Publicado: (2020)

A water-forming NADH oxidase from Lactobacillus pentosus suitable for the regeneration of synthetic biomimetic cofactors
por: Nowak, Claudia, et al.
Publicado: (2015)

Nanoreactors for green catalysis
por: De Martino, M Teresa, et al.
Publicado: (2018)

Cofactor engineering to regulate NAD(+)/NADH ratio with its application to phytosterols biotransformation
por: Su, Liqiu, et al.
Publicado: (2017)

Codon-Optimized NADH Oxidase Gene Expression and Gene Fusion with Glycerol Dehydrogenase for Bienzyme System with Cofactor Regeneration
por: Fang, Baishan, et al.
Publicado: (2015)

Biocatalytic hydroxylation of n-butane with in situ cofactor regeneration at low temperature and under normal pressure
por: Staudt, Svenja, et al.
Publicado: (2012)

Turn air-captured CO(2) with methanol into amino acid and pyruvate in an ATP/NAD(P)H-free chemoenzymatic system
por: Liu, Jianming, et al.
Publicado: (2023)

Chemoenzymatic Synthesis of Tenofovir
por: Zdun, Beata, et al.
Publicado: (2023)

Enzyme‐Loaded Nanoreactors Enable the Continuous Regeneration of Nicotinamide Adenine Dinucleotide in Artificial Metabolisms
por: Jo, Seong‐Min, et al.
Publicado: (2021)

Minimal Pathway for the Regeneration of Redox Cofactors
por: Partipilo, Michele, et al.
Publicado: (2021)

Mutations of an NAD(P)H-dependent flavoprotein monooxygenase that influence cofactor promiscuity and enantioselectivity()
por: Jensen, Chantel N., et al.
Publicado: (2013)

A Regulatory Role of NAD Redox Status on Flavin Cofactor Homeostasis in S. cerevisiae Mitochondria
por: Giancaspero, Teresa Anna, et al.
Publicado: (2013)

Structural Basis of Redox-Sensing Transcriptional Repressor Rex with Cofactor NAD(+) and Operator DNA
por: Jeong, Kang Hwa, et al.
Publicado: (2022)

Tip-induced nanoreactor for silicate
por: Gao, Ming, et al.
Publicado: (2015)

Delineating the phenotypic spectrum of sulfite oxidase and molybdenum cofactor deficiency
por: Misko, Albert L., et al.
Publicado: (2020)

In situ growth of ZnO nanoparticles in precursor-insensitive water-in-oil microemulsion as soft nanoreactors
por: Bumajdad, Ali, et al.
Publicado: (2015)

Network-wide thermodynamic constraints shape NAD(P)H cofactor specificity of biochemical reactions
por: Bekiaris, Pavlos Stephanos, et al.
Publicado: (2023)

Mining the cellular inventory of pyridoxal phosphate-dependent enzymes with functionalized cofactor mimics
por: Hoegl, Annabelle, et al.
Publicado: (2018)

Orthogonal glycolytic pathway enables directed evolution of noncanonical cofactor oxidase
por: King, Edward, et al.
Publicado: (2022)

Discovering chemistry with an ab initio nanoreactor
por: Wang, Lee-Ping, et al.
Publicado: (2014)

Substrate Sorting by a Supercharged Nanoreactor
por: Azuma, Yusuke, et al.
Publicado: (2017)

Catalyzed Bimolecular Reactions in Responsive Nanoreactors
por: Roa, Rafael, et al.
Publicado: (2017)

Directional coupling in spatially distributed nanoreactors
por: Das, Nirmali Prabha, et al.
Publicado: (2019)

Fueling genome maintenance: On the versatile roles of NAD(+) in preserving DNA integrity
por: Ruszkiewicz, Joanna A., et al.
Publicado: (2022)

Developing and enhancing promiscuous activity for NAD(P)H-dependent flavin reductase via elimination of cofactor
por: Navaser, Amene, et al.
Publicado: (2023)

Customizing Functionalized Cofactor Mimics to Study the Human Pyridoxal 5′-Phosphate-Binding Proteome
por: Fux, Anja, et al.
Publicado: (2019)

Going Full Circle with Organocatalysis and Biocatalysis: The Latent Potential of Cofactor Mimics in Asymmetric Synthesis
por: Murray, Jacob, et al.
Publicado: (2023)

Enzymology of Ca(2+)-Mobilizing Second Messengers Derived from NAD: From NAD Glycohydrolases to (Dual) NADPH Oxidases
por: Guse, Andreas H.
Publicado: (2023)

Chemoenzymatic Synthesis of Oligohyaluronan–Lipid Conjugates
por: Ruhela, Dipali, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_egbdbs4cgn3n99pe2dnqdg2qut