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Diversity of NKG2C genotypes in a European population: Conserved and recombinant haplotypes in the coding, promoter, and 3′‐untranslated regions

NK cells monitor altered molecular patterns in tumors and infected cells through an ample array of receptors. Two families of evolutionarily distant receptors have converged to enable human NK cells to sense levels of HLA class I ligands, frequently abnormal in altered cells. Whilst different forms...

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Detalles Bibliográficos
Autores principales: Asenjo, Judit, Moraru, Manuela, Al‐Akioui‐Sanz, Karima, Altadill, Mireia, Muntasell, Aura, López‐Botet, Miguel, Vilches, Carlos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9796621/
https://www.ncbi.nlm.nih.gov/pubmed/35802353
http://dx.doi.org/10.1111/tan.14734