Cargando…
Espin overexpression causes stereocilia defects and provides an anti‐capping effect on actin polymerization
Stereocilia are actin‐based projections of hair cells that are arranged in a step like array, in rows of increasing height, and that constitute the mechanosensory organelle used for the senses of hearing and balance. In order to function properly, stereocilia must attain precise sizes in different h...
Autores principales: | Zheng, Lili, Adam, Stephen A., García‐Anoveros, Jaime, Mitchell, Brian J., Bartles, James R. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons, Inc.
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9796729/ https://www.ncbi.nlm.nih.gov/pubmed/35844198 http://dx.doi.org/10.1002/cm.21719 |
Ejemplares similares
-
Characterization and regulation of an additional actin-filament-binding site in large isoforms of the stereocilia actin-bundling protein espin
por: Zheng, Lili, et al.
Publicado: (2014) -
Roles of the Espin Actin-Bundling Proteins in the Morphogenesis and Stabilization of Hair Cell Stereocilia Revealed in CBA/CaJ Congenic Jerker Mice
por: Sekerková, Gabriella, et al.
Publicado: (2011) -
The role of Espin in the stereocilia regeneration and protection in Atoh1‐overexpressed cochlear epithelium
por: Yang, Xuechun, et al.
Publicado: (2023) -
Espin cross-links cause the elongation of microvillus-type parallel actin bundles in vivo
por: Loomis, Patricia A., et al.
Publicado: (2003) -
Myosin IIIa boosts elongation of stereocilia by transporting espin 1 to the plus ends of actin filaments
por: Salles, Felipe T., et al.
Publicado: (2009)