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ECG Evaluation as Part of the Clinical Pharmacology Strategy in the Development of New Drugs: A Review of Current Practices and Opportunities Based on Five Case Studies

The International Conference on Harmonization (ICH) E14 document was revised in 2015 to allow concentration–corrected QT interval (C–QTc) analysis to be applied to data from early clinical pharmacology studies to exclude a small drug‐induced effect on QTc. Provided sufficiently high concentrations o...

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Detalles Bibliográficos
Autores principales:	Darpo, Borje, Borin, Marie, Ferber, Georg, Galluppi, Gerald R., Hopkins, Seth C., Landry, Ishani, Lo, Arthur, Rege, Bhaskar, Reyderman, Larisa, Sun, Lei, Watanabe, Takao, Xue, Hongqi, Yasuda, Sally
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2022
Materias:	Editor's Choice: Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9796926/ https://www.ncbi.nlm.nih.gov/pubmed/35665514 http://dx.doi.org/10.1002/jcph.2095

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