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Detailed Insights into the Inhibitory Mechanism of New Ebselen Derivatives against Main Protease (M(pro)) of Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2)

[Image: see text] SARS-CoV-2 main protease (M(pro)/3CL(pro)) is a crucial target for therapeutics, which is responsible for viral polyprotein cleavage and plays a vital role in virus replication and survival. Recent studies suggest that 2-phenylbenzisoselenazol-3(2H)-one (ebselen) is a potent covale...

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Detalles Bibliográficos
Autores principales:	Sahoo, Pritiranjan, Lenka, Dipti Ranjan, Batabyal, Monojit, Pain, Pritam Kumar, Kumar, Sangit, Manna, Debasish, Kumar, Atul
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2022
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9797022/ https://www.ncbi.nlm.nih.gov/pubmed/36650888 http://dx.doi.org/10.1021/acsptsci.2c00203

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