Cargando…

Obesity and Hyperphagia With Increased Defective ACTH: A Novel POMC Variant

OBJECTIVE: Patients with pro-opiomelanocortin (POMC) defects generally present with early-onset obesity, hyperphagia, hypopigmentation and adrenocorticotropin (ACTH) deficiency. Rodent models suggest that adequate cleavage of ACTH to α-melanocortin–stimulating hormone (α-MSH) and desacetyl-α-melanoc...

Descripción completa

Detalles Bibliográficos
Autores principales:	van der Valk, Eline S, Kleinendorst, Lotte, Delhanty, Patric J D, van der Voorn, Bibian, Visser, Jenny A, van Haelst, M M, de Graaff, Laura C G, Huisman, Martin, White, Anne, Ito, Shosuke, Wakamatsu, Kazumasa, de Rijke, Yolanda B, van den Akker, Erica L T, Iyer, Anand M, van Rossum, Elisabeth F C
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2022
Materias:	Online Only Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9797039/ https://www.ncbi.nlm.nih.gov/pubmed/35737586 http://dx.doi.org/10.1210/clinem/dgac342

Ejemplares similares

Effects of glucagon‐like peptide‐1 analogue treatment in genetic obesity: A case series
por: Welling, Mila S., et al.
Publicado: (2021)

Effects of Glucagon-Like-Peptide-1 Analogue Treatment in Genetic Obesity
por: Welling, Mila Sofie, et al.
Publicado: (2021)

OR14-2 Age of Onset of Obesity and Childhood BMI Trajectories in Rare Genetic Obesity Disorders
por: Brandsma, Annelies E, et al.
Publicado: (2022)

Glucocorticoids, stress and eating: The mediating role of appetite‐regulating hormones
por: Kuckuck, Susanne, et al.
Publicado: (2022)

A comprehensive diagnostic approach to detect underlying causes of obesity in adults
por: van der Valk, Eline S., et al.
Publicado: (2019)

Cross‐sectional relation of long‐term glucocorticoids in hair with anthropometric measurements and their possible determinants: A systematic review and meta‐analysis
por: van der Valk, Eline, et al.
Publicado: (2021)

Identifying underlying medical causes of pediatric obesity: Results of a systematic diagnostic approach in a pediatric obesity center
por: Kleinendorst, Lotte, et al.
Publicado: (2020)

Identifying underlying medical causes of pediatric obesity: Results of a systematic diagnostic approach in a pediatric obesity center
por: Kleinendorst, Lotte, et al.
Publicado: (2020)

Hair Cortisol, Obesity and the Immune System: Results From a 3 Year Longitudinal Study
por: van der Valk, Eline S, et al.
Publicado: (2021)

The Relation Between Cortisol and Anthropometric Measurements Throughout Lifespan: A Systematic Review and Meta-Analysis
por: van der Valk, Eline S, et al.
Publicado: (2021)

Variation in glucocorticoid sensitivity and the relation with obesity
por: Lengton, Robin, et al.
Publicado: (2021)

Impact of the COVID-19 Pandemic and Related Lockdown Measures on Lifestyle Behaviors and Well-Being in Children and Adolescents with Severe Obesity
por: Welling, Mila S., et al.
Publicado: (2021)

Resting Energy Expenditure and Body Composition in Children and Adolescents With Genetic, Hypothalamic, Medication-Induced or Multifactorial Severe Obesity
por: Abawi, Ozair, et al.
Publicado: (2022)

RF02 | PSAT110 Resting Energy Expenditure and Body Composition in Children and Adolescents with Genetic, Hypothalamic, Medication-Induced or Multifactorial Severe Obesity
por: Abawi, Ozair, et al.
Publicado: (2022)

The Narrative of a Patient with Leptin Receptor Deficiency: Personalized Medicine for a Rare Genetic Obesity Disorder
por: Welling, Mila S., et al.
Publicado: (2023)

Dextroamphetamine Treatment for Children With Hypothalamic Obesity
por: van Schaik, Jiska, et al.
Publicado: (2021)

COVID‐19 related anxiety in children and adolescents with severe obesity: A mixed‐methods study
por: Abawi, Ozair, et al.
Publicado: (2020)

Impact of Covid-19 Lockdown Measures on Lifestyle Behavior in Children and Adolescents With Severe Obesity
por: Abawi, Ozair, et al.
Publicado: (2021)

Successful naltrexone-bupropion treatment after several treatment failures in a patient with severe monogenic obesity
por: Welling, Mila S., et al.
Publicado: (2023)

Interpretation of glucocorticoids in neonatal hair: a reflection of intrauterine glucocorticoid regulation?
por: Hollanders, Jonneke J, et al.
Publicado: (2017)

RF09 | PSAT88 Pro-opiomelanocortin (POMC), ACTH and Cortisol Responses to Pediatric Cardiac Surgery
por: Téblick, Arno, et al.
Publicado: (2022)

Effects of RXR Agonists on Cell Proliferation/Apoptosis and ACTH Secretion/Pomc Expression
por: Saito-Hakoda, Akiko, et al.
Publicado: (2015)

Who ever heard of 16p11.2 deletion syndrome? Parents’ perspectives on a susceptibility copy number variation syndrome
por: Kleinendorst, Lotte, et al.
Publicado: (2020)

Hyperphagia, Growth, and Puberty in Children with Angelman Syndrome
por: Bindels-de Heus, Karen G. C. B., et al.
Publicado: (2023)

Stress and Obesity: Are There More Susceptible Individuals?
por: van der Valk, Eline S., et al.
Publicado: (2018)

Genetic analysis in the bariatric clinic; impact of a PTEN gene mutation
por: Cooiman, Mellody I., et al.
Publicado: (2019)

SAT027 Novel Obesity-Associated Melanocortin 4 Receptor Variants Modulate Signaling Differently
por: Rodriguez Rondon, Alejandra V, et al.
Publicado: (2023)

The Diagnostic Journey of a Patient with Prader–Willi-Like Syndrome and a Unique Homozygous SNURF-SNRPN Variant; Bio-Molecular Analysis and Review of the Literature
por: Pellikaan, Karlijn, et al.
Publicado: (2021)

Health-related quality of life in children under treatment for overweight, obesity or severe obesity: a cross-sectional study in the Netherlands
por: van der Voorn, Bibian, et al.
Publicado: (2023)

Improved Physical and Mental Health After a Combined Lifestyle Intervention with Cognitive Behavioural Therapy for Obesity
por: Mohseni, Mostafa, et al.
Publicado: (2022)

Overweight and obesity in type 1 diabetes is not associated with higher ghrelin concentrations
por: Özcan, Behiye, et al.
Publicado: (2021)

Weight-biased attitudes about pediatric patients with obesity in Dutch healthcare professionals from seven different professions
por: van der Voorn, Bibian, et al.
Publicado: (2023)

An exploratory study of perinatal hair cortisol concentrations in mother–infant dyads with severe psychiatric disorders versus healthy controls
por: Broeks, Carlinde W., et al.
Publicado: (2021)

Is HPA axis reactivity in childhood gender-specific? A systematic review
por: Hollanders, Jonneke J., et al.
Publicado: (2017)

OR24-02 Identification of Membrane Proteins That Enhance the Responsiveness of the Ghrelin Receptor
por: Prins, Karina, et al.
Publicado: (2020)

Plasma acylated and plasma unacylated ghrelin: useful new biomarkers in patients with neuroendocrine tumors?
por: van Adrichem, Roxanne C S, et al.
Publicado: (2016)

Loss of hypothalamic Furin affects POMC to proACTH cleavage and feeding behavior in high-fat diet-fed mice
por: Coppola, Ilaria, et al.
Publicado: (2022)

ODP607 Long-term Efficacy of Setmelanotide in Patients With POMC or LEPR Deficiency Obesity
por: Clément, Karine, et al.
Publicado: (2022)

Biochemical Mechanism of Rhododendrol-Induced Leukoderma
por: Ito, Shosuke, et al.
Publicado: (2018)

Recent Advances in Characterization of Melanin Pigments in Biological Samples
por: Wakamatsu, Kazumasa, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_50ifd1b46cre6vqbcp67579lvu