An extended SARS-CoV-2 mRNA vaccine prime-boost interval enhances B cell immunity with limited impact on T cells

Spacing the first two doses of SARS-CoV-2 mRNA vaccines beyond 3–4 weeks raised initial concerns about vaccine efficacy. While studies have since shown that long-interval regimens induce robust antibody responses, their impact on B and T cell immunity is poorly known. Here, we compare SARS-CoV-2 nai...

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Detalles Bibliográficos
Autores principales: Nicolas, Alexandre, Sannier, Gérémy, Dubé, Mathieu, Nayrac, Manon, Tauzin, Alexandra, Painter, Mark M., Goel, Rishi R., Laporte, Mélanie, Gendron-Lepage, Gabrielle, Medjahed, Halima, Williams, Justine C., Brassard, Nathalie, Niessl, Julia, Gokool, Laurie, Morrisseau, Chantal, Arlotto, Pascale, Tremblay, Cécile, Martel-Laferrière, Valérie, Finzi, Andrés, Greenplate, Allison R., Wherry, E. John, Kaufmann, Daniel E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9797215/
https://www.ncbi.nlm.nih.gov/pubmed/36594081
http://dx.doi.org/10.1016/j.isci.2022.105904

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