Persistent Severe Hyperlactatemia and Metabolic Derangement in Lethal SDHB-Mutated Metastatic Kidney Cancer: Clinical Challenges and Examples of Extreme Warburg Effect

To describe the unique clinical features, determine the genomics, and investigate the metabolic derangement of an extremely rare form of a hereditary lethal kidney cancer syndrome. PATIENTS AND METHODS: Three patients with lethal kidney cancer (age 19, 20, and 37 years) exhibiting persistent (1 to 3...

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Detalles Bibliográficos
Autores principales: Lee, Chung-Han, Gundem, Gunes, Lee, William, Chen, Ying-Bei, Cross, Justin R., Dong, Yiyu, Redzematovic, Almedina, Mano, Roy, Wei, Elizabeth Y., Cheng, Emily H., Srinivasan, Ramaprasad, Oschwald, Dayna, Hakimi, A. Ari, Dunphy, Mark P., Linehan, W. Marston, Papaemmanuil, Elli, Hsieh, James J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Clinical Oncology 2017
Materias:
Original Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9797236/
https://www.ncbi.nlm.nih.gov/pubmed/35172488
http://dx.doi.org/10.1200/PO.16.00007

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