Rosiglitazone Protects against Acetaminophen-Induced Acute Liver Injury by Inhibiting Multiple Endoplasmic Reticulum Stress Pathways

BACKGROUND: Excessive acetaminophen (APAP) use can lead to acute liver injury (ALI) by inducing endoplasmic reticulum stress (ERS). We previously found that pretreatment with the peroxisome proliferator-activated receptor-γ (PPAR-γ) ligand rosiglitazone (RSG) alleviated ALI in APAP-treated mice. OBJ...

Descripción completa

Detalles Bibliográficos
Autores principales: Cao, Yuping, He, Wei, Li, Xiaoping, Huang, Jiahui, Wang, Junxian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9797312/
https://www.ncbi.nlm.nih.gov/pubmed/36588533
http://dx.doi.org/10.1155/2022/6098592

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9797312/
https://www.ncbi.nlm.nih.gov/pubmed/36588533
http://dx.doi.org/10.1155/2022/6098592

Ejemplares similares