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Rosiglitazone Protects against Acetaminophen-Induced Acute Liver Injury by Inhibiting Multiple Endoplasmic Reticulum Stress Pathways

BACKGROUND: Excessive acetaminophen (APAP) use can lead to acute liver injury (ALI) by inducing endoplasmic reticulum stress (ERS). We previously found that pretreatment with the peroxisome proliferator-activated receptor-γ (PPAR-γ) ligand rosiglitazone (RSG) alleviated ALI in APAP-treated mice. OBJ...

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Detalles Bibliográficos
Autores principales:	Cao, Yuping, He, Wei, Li, Xiaoping, Huang, Jiahui, Wang, Junxian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9797312/ https://www.ncbi.nlm.nih.gov/pubmed/36588533 http://dx.doi.org/10.1155/2022/6098592

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