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Cutaneous presentation of metastatic pancreatic cancer
Pancreatic cancer typically presents with a cholestatic picture of jaundice, bloating and bowel changes, secondary to the obstruction of the biliary system. In tail of pancreas metastases, this clinical presentation may be absent, meaning that the disease progression can be more insidious. Cutaneous...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9797327/ https://www.ncbi.nlm.nih.gov/pubmed/36589687 http://dx.doi.org/10.1093/jscr/rjac589 |
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author | Abdelaziz, Mohammed Thorley, Daniel Ahmed, Waseem |
author_facet | Abdelaziz, Mohammed Thorley, Daniel Ahmed, Waseem |
author_sort | Abdelaziz, Mohammed |
collection | PubMed |
description | Pancreatic cancer typically presents with a cholestatic picture of jaundice, bloating and bowel changes, secondary to the obstruction of the biliary system. In tail of pancreas metastases, this clinical presentation may be absent, meaning that the disease progression can be more insidious. Cutaneous spread in pancreatic malignancies is often iatrogenic due to direct spread from the tumour site during diagnostic sampling or surgery. Rarely, cutaneous spread can be noted at distant sites, which is associated with widespread disease dissemination and poor prognostic outcomes. Our case focusses on a patient who developed metastatic spread to the chin, as a first presentation, with no other significant associated symptoms identified. |
format | Online Article Text |
id | pubmed-9797327 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Oxford University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-97973272022-12-30 Cutaneous presentation of metastatic pancreatic cancer Abdelaziz, Mohammed Thorley, Daniel Ahmed, Waseem J Surg Case Rep Case Report Pancreatic cancer typically presents with a cholestatic picture of jaundice, bloating and bowel changes, secondary to the obstruction of the biliary system. In tail of pancreas metastases, this clinical presentation may be absent, meaning that the disease progression can be more insidious. Cutaneous spread in pancreatic malignancies is often iatrogenic due to direct spread from the tumour site during diagnostic sampling or surgery. Rarely, cutaneous spread can be noted at distant sites, which is associated with widespread disease dissemination and poor prognostic outcomes. Our case focusses on a patient who developed metastatic spread to the chin, as a first presentation, with no other significant associated symptoms identified. Oxford University Press 2022-12-28 /pmc/articles/PMC9797327/ /pubmed/36589687 http://dx.doi.org/10.1093/jscr/rjac589 Text en Published by Oxford University Press and JSCR Publishing Ltd. All rights reserved. © The Author(s) 2022. https://creativecommons.org/licenses/by-nc/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (https://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com |
spellingShingle | Case Report Abdelaziz, Mohammed Thorley, Daniel Ahmed, Waseem Cutaneous presentation of metastatic pancreatic cancer |
title | Cutaneous presentation of metastatic pancreatic cancer |
title_full | Cutaneous presentation of metastatic pancreatic cancer |
title_fullStr | Cutaneous presentation of metastatic pancreatic cancer |
title_full_unstemmed | Cutaneous presentation of metastatic pancreatic cancer |
title_short | Cutaneous presentation of metastatic pancreatic cancer |
title_sort | cutaneous presentation of metastatic pancreatic cancer |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9797327/ https://www.ncbi.nlm.nih.gov/pubmed/36589687 http://dx.doi.org/10.1093/jscr/rjac589 |
work_keys_str_mv | AT abdelazizmohammed cutaneouspresentationofmetastaticpancreaticcancer AT thorleydaniel cutaneouspresentationofmetastaticpancreaticcancer AT ahmedwaseem cutaneouspresentationofmetastaticpancreaticcancer |