Integration of ER protein quality control mechanisms defines β cell function and ER architecture

Three principal ER quality-control mechanisms, namely, the unfolded protein response, ER-associated degradation (ERAD), and ER-phagy are each important for the maintenance of ER homeostasis, yet how they are integrated to regulate ER homeostasis and organellar architecture in vivo is largely unclear...

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Detalles Bibliográficos
Autores principales: Shrestha, Neha, Torres, Mauricio, Zhang, Jason, Lu, You, Haataja, Leena, Reinert, Rachel B., Knupp, Jeffrey, Chen, Yu-Jie, Parlakgul, Gunes, Arruda, Ana Paula, Tsai, Billy, Arvan, Peter, Qi, Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9797341/
https://www.ncbi.nlm.nih.gov/pubmed/36346671
http://dx.doi.org/10.1172/JCI163584

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