Roles of the functional domains and conserved residues of the severe fever with thrombocytopenia syndrome virus L protein provide insights into the viral RNA transcription/replication mechanism

• All the domains of SFTSV-L protein were required for its function in viral RNA replication/transcription. • The influence of twelve conserved residues were evaluated, nine of which showed significance in the function of L protein. • Nine residues of SFTSV-L were strictly conserved among phleboviru...

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Detalles Bibliográficos
Autores principales: Yin, Zhiyun, Ren, Fuli, Zhou, Min, Chen, Shengyao, Deng, Yali, Hu, Sijing, Deng, Fei, Shen, Shu, Shi, Junming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wuhan Institute of Virology, Chinese Academy of Sciences 2022
Materias:
Letter
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9797366/
https://www.ncbi.nlm.nih.gov/pubmed/36064095
http://dx.doi.org/10.1016/j.virs.2022.08.009

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