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CK1α upregulates the IFNAR1 expression to prompt the anti-HBV effect of type I IFN in hepatoma carcinoma cells

Casein kinase 1α (CK1α) mediates the phosphorylation and degradation of interferon-α/β receptor 1 (IFNAR1) in response to viral infection. However, how CK1α regulates hepatitis B virus (HBV) replication and the anti-HBV effects of IFN-α are less reported. Here we show that CK1α can interact with IFN...

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Detalles Bibliográficos
Autores principales:	Xiong, Jing, Jiang, Yanjun, Zhang, Jinru, Chen, Yanmeng, Hu, Yuan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Wuhan Institute of Virology, Chinese Academy of Sciences 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9797371/ https://www.ncbi.nlm.nih.gov/pubmed/35985475 http://dx.doi.org/10.1016/j.virs.2022.08.004

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