Cargando…

Computational analysis to define efficacy & molecular mechanisms of 7, 4’- Dihydroxyflavone on eosinophilic esophagitis: Ex-vivo validation in human esophagus biopsies

INTRODUCTION: Eosinophilic Esophagitis (EoE) is a chronic condition characterized by eosinophilic inflammation of the esophagus which leads to esophageal dysfunction with common symptoms including vomiting, feeding difficulty, dysphagia, abdominal pain. Current main treatment options of EoE include...

Descripción completa

Detalles Bibliográficos
Autores principales:	Maskey, Anish R., Wang, Zhen-Zhen, Chen, Xin, Dunkin, David, Yang, Nan, Soffer, Gary, Yuan, Qian, Li, Xiu-Min
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9797535/ https://www.ncbi.nlm.nih.gov/pubmed/36591238 http://dx.doi.org/10.3389/fimmu.2022.1015437

Ejemplares similares

Induction of Severe Eosinophilic Esophagitis and Multi-Organ Inflammation by Airborne Allergens is Associated with IL-4/IL-13 and CCL11 but Not IgE in Genetic Susceptible Mice
por: Maskey, Anish, et al.
Publicado: (2022)

The Slender Esophagus: Unrecognized Esophageal Narrowing in Eosinophilic Esophagitis
por: Lynch, Kristle L., et al.
Publicado: (2023)

Pediatric Patient With Concurrent Eosinophilic Esophagitis, Erosive Reflux Esophagitis, and Barrett's Esophagus
por: Sharma, Ishna, et al.
Publicado: (2020)

Activated Eosinophils are Present in Esophageal Muscle in Patients with Achalasia of the Esophagus
por: Jin, Hong, et al.
Publicado: (2018)

From eosinophilic esophagitis to esophagus perforation: clinical management strategies
por: Scutaru, Tabita Timeea, et al.
Publicado: (2021)

Proposed criteria to differentiate heterogeneous eosinophilic gastrointestinal disorders of the esophagus, including eosinophilic esophageal myositis
por: Sato, Hiroki, et al.
Publicado: (2017)

Successful Management of Eosinophilic Esophagitis Using Traditional Chinese Medicine: A Case Report
por: Soffer, Gary, et al.
Publicado: (2020)

How does esophagus look on barium esophagram in pediatric eosinophilic esophagitis?
por: Al-Hussaini, Abdulrahman, et al.
Publicado: (2016)

Rings in the esophagus are not always eosinophilic esophagitis: Case series of ring forming lymphocytic esophagitis and review of the literature
por: Pleet, Julia L., et al.
Publicado: (2017)

Characterizing the inflammatory response in esophageal mucosal biopsies in children with eosinophilic esophagitis
por: Sayej, Wael N, et al.
Publicado: (2016)

7,8-Dihydroxyflavone Protects High Glucose-Damaged Neuronal Cells against Oxidative Stress
por: Cho, Suk Ju, et al.
Publicado: (2019)

Disease-associated DNA methylation signatures in esophageal biopsies of children diagnosed with Eosinophilic Esophagitis
por: Strisciuglio, Caterina, et al.
Publicado: (2021)

7,8-Dihydroxyflavone Enhances Cue-Conditioned Alcohol Reinstatement in Rats
por: Hogarth, Samuel J., et al.
Publicado: (2020)

Eosinophilic esophagitis in esophageal atresia: Tertiary care experience of a “selective” approach for biopsy sampling
por: Tambucci, Renato, et al.
Publicado: (2020)

Aging impairs dendrite morphogenesis of newborn neurons and is rescued by 7, 8‐dihydroxyflavone
por: Wang, Xiaoting, et al.
Publicado: (2017)

Synapse‐selective rapid potentiation of hippocampal synaptic transmission by 7,8‐dihydroxyflavone
por: Kobayashi, Katsunori, et al.
Publicado: (2018)

Baicalein, 7,8-Dihydroxyflavone and Myricetin as Potent Inhibitors of Human Ornithine Decarboxylase
por: Liu, Yun-Chin, et al.
Publicado: (2020)

The TrkB agonist, 7,8-dihydroxyflavone, impairs fracture healing in mice
por: Johnstone, Maddison R., et al.
Publicado: (2021)

Eosinophilic esophagitis
por: Carr, Stuart, et al.
Publicado: (2011)

Eosinophilic esophagitis
por: Carr, Stuart, et al.
Publicado: (2018)

Esophageal Microbiome in Eosinophilic Esophagitis
por: Harris, J. Kirk, et al.
Publicado: (2015)

Eosinophilic Esophagitis in Esophageal Atresia
por: Krishnan, Usha
Publicado: (2019)

Eosinophilic esophagitis and esophageal microbiota
por: Zhang, Xiaohan, et al.
Publicado: (2023)

The Effect of Root Exudate 7,4′-Dihydroxyflavone and Naringenin on Soil Bacterial Community Structure
por: Szoboszlay, Márton, et al.
Publicado: (2016)

Neuroprotective Effects of 7, 8-dihydroxyflavone on Midbrain Dopaminergic Neurons in MPP(+)-treated Monkeys
por: He, Jingjing, et al.
Publicado: (2016)

7,8-Dihydroxyflavone modulates bone formation and resorption and ameliorates ovariectomy-induced osteoporosis
por: Xue, Fan, et al.
Publicado: (2021)

Metabolic protection by the dietary flavonoid 7,8-dihydroxyflavone requires an intact gut microbiome
por: Sharma, Priyanka, et al.
Publicado: (2022)

Rescue of Long-Term Spatial Memory by 7,8-Dihydroxyflavone in Mice with Reduced Oligodendrogenesis
por: Rawlings-Mortimer, Florence, et al.
Publicado: (2023)

Alteration of the esophageal microbiota in Barrett's esophagus and esophageal adenocarcinoma
por: Lv, Jing, et al.
Publicado: (2019)

Benign Tumors of the Esophagus: A Histopathologic Study of 49 Cases among 931 Consecutive Esophageal Biopsies
por: Terada, Tadashi
Publicado: (2009)

Food‐specific IgA levels in esophageal biopsies are not sufficiently high to predict food triggers in eosinophilic esophagitis
por: Abramson, Lior, et al.
Publicado: (2023)

Butanol Purified Food Allergy Herbal Formula-2 Has an Immunomodulating Effect ex-vivo in Pediatric Crohn's Disease Subjects
por: Chen, Xin, et al.
Publicado: (2021)

Acute Esophageal Necrosis: “Black Esophagus”
por: Hwang, Joanna, et al.
Publicado: (2007)

Chemoprevention in Barrett’s esophagus and esophageal adenocarcinoma
por: Alkhayyat, Motasem, et al.
Publicado: (2021)

Cytochrome P450 3A4 suppression by epimedium and active compound kaempferol leads to synergistic anti-inflammatory effect with corticosteroid
por: Li, Ke, et al.
Publicado: (2023)

Effect of 7,8-Dihydroxyflavone as an Antioxidant on In Vitro Maturation of Oocytes and Development of Parthenogenetic Embryos in Pigs
por: CHOI, Ji-Yei, et al.
Publicado: (2013)

Effects of chrysin (5,7-dihydroxyflavone) on vascular remodeling in hypoxia-induced pulmonary hypertension in rats
por: Li, Xian-Wei, et al.
Publicado: (2015)

7,8-Dihydroxyflavone Protects Nigrostriatal Dopaminergic Neurons from Rotenone-Induced Neurotoxicity in Rodents
por: Nie, Shuke, et al.
Publicado: (2019)

Low-dose 7,8-Dihydroxyflavone Administration After Status Epilepticus Prevents Epilepsy Development
por: Guarino, Annunziata, et al.
Publicado: (2022)

7,8-Dihydroxyflavone and Neuropsychiatric Disorders: A Translational Perspective from the Mechanism to Drug Development
por: Yang, Shaojie, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_l3tv7sf6nju4aibonpdq30m0g0