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Endothelial dysfunction in Marfan syndrome mice is restored by resveratrol

Patients with Marfan syndrome (MFS) develop thoracic aortic aneurysms as the aorta presents excessive elastin breaks, fibrosis, and vascular smooth muscle cell (vSMC) death due to mutations in the FBN1 gene. Despite elaborate vSMC to aortic endothelial cell (EC) signaling, the contribution of ECs to...

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Detalles Bibliográficos
Autores principales:	Mieremet, Arnout, van der Stoel, Miesje, Li, Siyu, Coskun, Evrim, van Krimpen, Tsveta, Huveneers, Stephan, de Waard, Vivian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9797556/ https://www.ncbi.nlm.nih.gov/pubmed/36577770 http://dx.doi.org/10.1038/s41598-022-26662-5

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