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Multi-omics investigation reveals functional specialization of transcriptional cyclin dependent kinases in cancer biology

Transcriptional addiction is recognized as a valid therapeutic target in cancer, whereby the dependency of cancer cells on oncogenic transcriptional regulators may be pharmacologically exploited. However, a comprehensive understanding of the key factors within the transcriptional machinery that migh...

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Detalles Bibliográficos
Autores principales: Donovan, Micah G., Galbraith, Matthew D., Espinosa, Joaquin M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9797569/
https://www.ncbi.nlm.nih.gov/pubmed/36577800
http://dx.doi.org/10.1038/s41598-022-26860-1