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Multi-omics investigation reveals functional specialization of transcriptional cyclin dependent kinases in cancer biology
Transcriptional addiction is recognized as a valid therapeutic target in cancer, whereby the dependency of cancer cells on oncogenic transcriptional regulators may be pharmacologically exploited. However, a comprehensive understanding of the key factors within the transcriptional machinery that migh...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9797569/ https://www.ncbi.nlm.nih.gov/pubmed/36577800 http://dx.doi.org/10.1038/s41598-022-26860-1 |