Cargando…
Multi-omics investigation reveals functional specialization of transcriptional cyclin dependent kinases in cancer biology
Transcriptional addiction is recognized as a valid therapeutic target in cancer, whereby the dependency of cancer cells on oncogenic transcriptional regulators may be pharmacologically exploited. However, a comprehensive understanding of the key factors within the transcriptional machinery that migh...
Autores principales: | Donovan, Micah G., Galbraith, Matthew D., Espinosa, Joaquin M. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9797569/ https://www.ncbi.nlm.nih.gov/pubmed/36577800 http://dx.doi.org/10.1038/s41598-022-26860-1 |
Ejemplares similares
-
Therapeutic targeting of transcriptional cyclin-dependent kinases
por: Galbraith, Matthew D., et al.
Publicado: (2018) -
A Kinase-Independent Role for Cyclin-Dependent Kinase 19 in p53 Response
por: Audetat, K. Audrey, et al.
Publicado: (2017) -
Multi-omics analysis reveals contextual tumor suppressive and oncogenic gene modules within the acute hypoxic response
por: Andrysik, Zdenek, et al.
Publicado: (2021) -
Cyclin-dependent kinases
por: Malumbres, Marcos
Publicado: (2014) -
Transcription associated cyclin-dependent kinases as therapeutic targets for prostate cancer
por: Constantin, Theodora A., et al.
Publicado: (2022)