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Dysregulation of TSP2-Rac1-WAVE2 axis in diabetic cells leads to cytoskeletal disorganization, increased cell stiffness, and dysfunction

Fibroblasts are a major cell population that perform critical functions in the wound healing process. In response to injury, they proliferate and migrate into the wound space, engaging in extracellular matrix (ECM) production, remodeling, and contraction. However, there is limited knowledge of how f...

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Detalles Bibliográficos
Autores principales: Xing, Hao, Huang, Yaqing, Kunkemoeller, Britta H., Dahl, Peter J., Muraleetharan, Ohvia, Malvankar, Nikhil S., Murrell, Michael P., Kyriakides, Themis R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9797577/
https://www.ncbi.nlm.nih.gov/pubmed/36577792
http://dx.doi.org/10.1038/s41598-022-26337-1