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Dysregulation of TSP2-Rac1-WAVE2 axis in diabetic cells leads to cytoskeletal disorganization, increased cell stiffness, and dysfunction
Fibroblasts are a major cell population that perform critical functions in the wound healing process. In response to injury, they proliferate and migrate into the wound space, engaging in extracellular matrix (ECM) production, remodeling, and contraction. However, there is limited knowledge of how f...
Autores principales: | Xing, Hao, Huang, Yaqing, Kunkemoeller, Britta H., Dahl, Peter J., Muraleetharan, Ohvia, Malvankar, Nikhil S., Murrell, Michael P., Kyriakides, Themis R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9797577/ https://www.ncbi.nlm.nih.gov/pubmed/36577792 http://dx.doi.org/10.1038/s41598-022-26337-1 |
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