Cargando…
Prevalence of infectious diseases in preterm infants: a 2-year follow-up from the Japan Environment and Children’s Study
Evidence regarding the long-term risk of infections in preterm infants is lacking. In this study, we examined whether preterm infants developed various common childhood infections more frequently than full-term infants by the age of 2 years by analyzing data from a questionnaire completed by 67,282...
Autores principales: | , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9797578/ https://www.ncbi.nlm.nih.gov/pubmed/36577762 http://dx.doi.org/10.1038/s41598-022-26748-0 |
_version_ | 1784860712890269696 |
---|---|
author | Tamura, Kentaro Matsumura, Kenta Tsuchida, Akiko Yoshida, Taketoshi Inadera, Hidekuni |
author_facet | Tamura, Kentaro Matsumura, Kenta Tsuchida, Akiko Yoshida, Taketoshi Inadera, Hidekuni |
author_sort | Tamura, Kentaro |
collection | PubMed |
description | Evidence regarding the long-term risk of infections in preterm infants is lacking. In this study, we examined whether preterm infants developed various common childhood infections more frequently than full-term infants by the age of 2 years by analyzing data from a questionnaire completed by 67,282 mother–toddler pairs in a nationwide birth cohort study. Of the target population, 2885 (4.3%) were born prematurely. After covariate adjustment for maternal and children factors, lower respiratory tract infections appeared more frequent in preterm than in full-term infants at both 1 and 2 years (adjusted odds ratio [aOR] 1.21, 95% confidence interval [CI] 1.05–1.41, and aOR 1.27, 95% CI 1.11–1.46, respectively). However, there was no significant difference in the frequencies of lower respiratory tract infection between preterm and full-term infants after Palivizumab administration. The risk of other common infections, such as in the upper respiratory tract infection, otitis media, urinary tract infection, gastroenteritis, herpangina, hand-foot-and-mouth disease, chickenpox, influenza virus, and adenovirus infections, was not higher in preterm than in full-term infants after covariates adjustment for maternal and children factors. These findings suggest Palivizumab prophylaxis could reduce the frequencies of lower respiratory tract infection in preterm to the same level as in full-term infants. |
format | Online Article Text |
id | pubmed-9797578 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Nature Publishing Group UK |
record_format | MEDLINE/PubMed |
spelling | pubmed-97975782022-12-30 Prevalence of infectious diseases in preterm infants: a 2-year follow-up from the Japan Environment and Children’s Study Tamura, Kentaro Matsumura, Kenta Tsuchida, Akiko Yoshida, Taketoshi Inadera, Hidekuni Sci Rep Article Evidence regarding the long-term risk of infections in preterm infants is lacking. In this study, we examined whether preterm infants developed various common childhood infections more frequently than full-term infants by the age of 2 years by analyzing data from a questionnaire completed by 67,282 mother–toddler pairs in a nationwide birth cohort study. Of the target population, 2885 (4.3%) were born prematurely. After covariate adjustment for maternal and children factors, lower respiratory tract infections appeared more frequent in preterm than in full-term infants at both 1 and 2 years (adjusted odds ratio [aOR] 1.21, 95% confidence interval [CI] 1.05–1.41, and aOR 1.27, 95% CI 1.11–1.46, respectively). However, there was no significant difference in the frequencies of lower respiratory tract infection between preterm and full-term infants after Palivizumab administration. The risk of other common infections, such as in the upper respiratory tract infection, otitis media, urinary tract infection, gastroenteritis, herpangina, hand-foot-and-mouth disease, chickenpox, influenza virus, and adenovirus infections, was not higher in preterm than in full-term infants after covariates adjustment for maternal and children factors. These findings suggest Palivizumab prophylaxis could reduce the frequencies of lower respiratory tract infection in preterm to the same level as in full-term infants. Nature Publishing Group UK 2022-12-28 /pmc/articles/PMC9797578/ /pubmed/36577762 http://dx.doi.org/10.1038/s41598-022-26748-0 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . |
spellingShingle | Article Tamura, Kentaro Matsumura, Kenta Tsuchida, Akiko Yoshida, Taketoshi Inadera, Hidekuni Prevalence of infectious diseases in preterm infants: a 2-year follow-up from the Japan Environment and Children’s Study |
title | Prevalence of infectious diseases in preterm infants: a 2-year follow-up from the Japan Environment and Children’s Study |
title_full | Prevalence of infectious diseases in preterm infants: a 2-year follow-up from the Japan Environment and Children’s Study |
title_fullStr | Prevalence of infectious diseases in preterm infants: a 2-year follow-up from the Japan Environment and Children’s Study |
title_full_unstemmed | Prevalence of infectious diseases in preterm infants: a 2-year follow-up from the Japan Environment and Children’s Study |
title_short | Prevalence of infectious diseases in preterm infants: a 2-year follow-up from the Japan Environment and Children’s Study |
title_sort | prevalence of infectious diseases in preterm infants: a 2-year follow-up from the japan environment and children’s study |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9797578/ https://www.ncbi.nlm.nih.gov/pubmed/36577762 http://dx.doi.org/10.1038/s41598-022-26748-0 |
work_keys_str_mv | AT tamurakentaro prevalenceofinfectiousdiseasesinpreterminfantsa2yearfollowupfromthejapanenvironmentandchildrensstudy AT matsumurakenta prevalenceofinfectiousdiseasesinpreterminfantsa2yearfollowupfromthejapanenvironmentandchildrensstudy AT tsuchidaakiko prevalenceofinfectiousdiseasesinpreterminfantsa2yearfollowupfromthejapanenvironmentandchildrensstudy AT yoshidataketoshi prevalenceofinfectiousdiseasesinpreterminfantsa2yearfollowupfromthejapanenvironmentandchildrensstudy AT inaderahidekuni prevalenceofinfectiousdiseasesinpreterminfantsa2yearfollowupfromthejapanenvironmentandchildrensstudy AT prevalenceofinfectiousdiseasesinpreterminfantsa2yearfollowupfromthejapanenvironmentandchildrensstudy |