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Microvascular assessment of fascio-cutaneous flaps by ultrasound: A large animal study
Objectives: Blood perfusion quality of a flap is the main prognostic factor for success. Microvascular evaluation remains mostly inaccessible. We aimed to evaluate the microflow imaging mode, MV-Flow, in assessing flap microvascularization in a pig model of the fascio-cutaneous flap. Methods: On fiv...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9797596/ https://www.ncbi.nlm.nih.gov/pubmed/36589429 http://dx.doi.org/10.3389/fphys.2022.1063240 |
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author | Goudot, Guillaume Berkane, Yanis de Clermont-Tonnerre, Eloi Guinier, Claire Filz von Reiterdank, Irina van Kampen, Antonia Uygun, Korkut Cetrulo, Curtis L. Uygun, Basak E. Dua, Anahita Lellouch, Alexandre G. |
author_facet | Goudot, Guillaume Berkane, Yanis de Clermont-Tonnerre, Eloi Guinier, Claire Filz von Reiterdank, Irina van Kampen, Antonia Uygun, Korkut Cetrulo, Curtis L. Uygun, Basak E. Dua, Anahita Lellouch, Alexandre G. |
author_sort | Goudot, Guillaume |
collection | PubMed |
description | Objectives: Blood perfusion quality of a flap is the main prognostic factor for success. Microvascular evaluation remains mostly inaccessible. We aimed to evaluate the microflow imaging mode, MV-Flow, in assessing flap microvascularization in a pig model of the fascio-cutaneous flap. Methods: On five pigs, bilateral saphenous fascio-cutaneous flaps were procured on the superficial femoral vessels. A conventional ultrasound evaluation in pulsed Doppler and color Doppler was conducted on the ten flaps allowing for the calculation of the saphenous artery flow rate. The MV-Flow mode was then applied: for qualitative analysis, with identification of saphenous artery collaterals; then quantitative, with repeated measurements of the Vascularity Index (VI), percentage of pixels where flow is detected relative to the total ultrasound view area. The measurements were then repeated after increasing arterial flow by clamping the distal femoral artery. Results: The MV-Flow mode allowed a better follow-up of the saphenous artery’s collaterals and detected microflows not seen with the color Doppler. The VI was correlated to the saphenous artery flow rate (Spearman rho of 0.64; p = 0.002) and allowed to monitor the flap perfusion variations. Conclusion: Ultrasound imaging of microvascularization by MV-Flow mode and its quantification by VI provides valuable information in evaluating the microvascularization of flaps. |
format | Online Article Text |
id | pubmed-9797596 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-97975962022-12-30 Microvascular assessment of fascio-cutaneous flaps by ultrasound: A large animal study Goudot, Guillaume Berkane, Yanis de Clermont-Tonnerre, Eloi Guinier, Claire Filz von Reiterdank, Irina van Kampen, Antonia Uygun, Korkut Cetrulo, Curtis L. Uygun, Basak E. Dua, Anahita Lellouch, Alexandre G. Front Physiol Physiology Objectives: Blood perfusion quality of a flap is the main prognostic factor for success. Microvascular evaluation remains mostly inaccessible. We aimed to evaluate the microflow imaging mode, MV-Flow, in assessing flap microvascularization in a pig model of the fascio-cutaneous flap. Methods: On five pigs, bilateral saphenous fascio-cutaneous flaps were procured on the superficial femoral vessels. A conventional ultrasound evaluation in pulsed Doppler and color Doppler was conducted on the ten flaps allowing for the calculation of the saphenous artery flow rate. The MV-Flow mode was then applied: for qualitative analysis, with identification of saphenous artery collaterals; then quantitative, with repeated measurements of the Vascularity Index (VI), percentage of pixels where flow is detected relative to the total ultrasound view area. The measurements were then repeated after increasing arterial flow by clamping the distal femoral artery. Results: The MV-Flow mode allowed a better follow-up of the saphenous artery’s collaterals and detected microflows not seen with the color Doppler. The VI was correlated to the saphenous artery flow rate (Spearman rho of 0.64; p = 0.002) and allowed to monitor the flap perfusion variations. Conclusion: Ultrasound imaging of microvascularization by MV-Flow mode and its quantification by VI provides valuable information in evaluating the microvascularization of flaps. Frontiers Media S.A. 2022-12-15 /pmc/articles/PMC9797596/ /pubmed/36589429 http://dx.doi.org/10.3389/fphys.2022.1063240 Text en Copyright © 2022 Goudot, Berkane, de Clermont-Tonnerre, Guinier, Filz von Reiterdank, van Kampen, Uygun, Cetrulo, Uygun, Dua and Lellouch. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Physiology Goudot, Guillaume Berkane, Yanis de Clermont-Tonnerre, Eloi Guinier, Claire Filz von Reiterdank, Irina van Kampen, Antonia Uygun, Korkut Cetrulo, Curtis L. Uygun, Basak E. Dua, Anahita Lellouch, Alexandre G. Microvascular assessment of fascio-cutaneous flaps by ultrasound: A large animal study |
title | Microvascular assessment of fascio-cutaneous flaps by ultrasound: A large animal study |
title_full | Microvascular assessment of fascio-cutaneous flaps by ultrasound: A large animal study |
title_fullStr | Microvascular assessment of fascio-cutaneous flaps by ultrasound: A large animal study |
title_full_unstemmed | Microvascular assessment of fascio-cutaneous flaps by ultrasound: A large animal study |
title_short | Microvascular assessment of fascio-cutaneous flaps by ultrasound: A large animal study |
title_sort | microvascular assessment of fascio-cutaneous flaps by ultrasound: a large animal study |
topic | Physiology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9797596/ https://www.ncbi.nlm.nih.gov/pubmed/36589429 http://dx.doi.org/10.3389/fphys.2022.1063240 |
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