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Pharmacokinetics, metabolite profiling, safety, and tolerability of inhalation aerosol of 101BHG-D01, a novel, long-acting and selective muscarinic receptor antagonist, in healthy Chinese subjects

101BHG-D01 is a novel, long-acting, selective muscarinic receptor antagonist for the treatment of chronic obstructive pulmonary disease (COPD). A single-site, randomized, double-blind, placebo-controlled and dose-escalation study of 101BHG-D01 inhalation aerosol was conducted to evaluate its pharmac...

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Detalles Bibliográficos
Autores principales:	Gao, Huaye, Li, Jintong, Chen, Xiaoping, Sun, Zhanguo, Cui, Gang, Cheng, Minlu, Ding, Li
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9797597/ https://www.ncbi.nlm.nih.gov/pubmed/36588683 http://dx.doi.org/10.3389/fphar.2022.1064364

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