HCMV carriage in the elderly diminishes anti-viral functionality of the adaptive immune response resulting in virus replication at peripheral sites

Human cytomegalovirus (HCMV) infection and periodic reactivation is, generally, well controlled by adaptative immune responses in the healthy. In older people, overt HCMV disease is rarely seen despite the association of HCMV with increased risk of mortality; evidence from studies of unwell aged pop...

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Detalles Bibliográficos
Autores principales: Davies, Emma L., Noor, Mahlaqua, Lim, Eleanor Y., Houldcroft, Charlotte J., Okecha, Georgina, Atkinson, Claire, Reeves, Matthew B., Jackson, Sarah E., Wills, Mark R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9797693/
https://www.ncbi.nlm.nih.gov/pubmed/36591233
http://dx.doi.org/10.3389/fimmu.2022.1083230

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9797693/
https://www.ncbi.nlm.nih.gov/pubmed/36591233
http://dx.doi.org/10.3389/fimmu.2022.1083230

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