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HCMV carriage in the elderly diminishes anti-viral functionality of the adaptive immune response resulting in virus replication at peripheral sites
Human cytomegalovirus (HCMV) infection and periodic reactivation is, generally, well controlled by adaptative immune responses in the healthy. In older people, overt HCMV disease is rarely seen despite the association of HCMV with increased risk of mortality; evidence from studies of unwell aged pop...
Autores principales: | Davies, Emma L., Noor, Mahlaqua, Lim, Eleanor Y., Houldcroft, Charlotte J., Okecha, Georgina, Atkinson, Claire, Reeves, Matthew B., Jackson, Sarah E., Wills, Mark R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9797693/ https://www.ncbi.nlm.nih.gov/pubmed/36591233 http://dx.doi.org/10.3389/fimmu.2022.1083230 |
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